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upper respiratory tract infection
IllnessWikipedia
14
MENTIONS
5
EPISODES
5
PODCASTS
Search complete. 14 mentions across 5 episodes found for "upper respiratory tract infection".
Sep 23, 2026
Danielle Gagne-PalomboHOST
No IBD signal, and the most common side effect was skin events, especially acne-like reactions, which we have seen in previous deucravacitinib studies as well, as well as infection, COVID, influenza.
Danielle Gagne-PalomboHOST
And then at week fifty-two, the most common side effects was nasopharyngitis, URI, hypertension, and UTI.
Danielle Gagne-PalomboHOST
So looking at this study overall, it was a great study.
Danielle Gagne-PalomboHOST
It's a gold standard trial design with that switch from placebo into an active comparator group, which really solidified the efficacy and durability of deucravacitinib.
Darrell ChutkaHOST
Yeah.
Darrell ChutkaHOST
Well, you've both kind of touched on this next question a little bit, but how do you distinguish between viral URIs, allergic rhinitis and and bacterial sinusitis, because they can all present with somewhat similar symptoms.
Rohit DivekarGUEST
Yeah, I mean, you've kind of really planned it nicely.
Rohit DivekarGUEST
It's very hard to really 100% say this is viral URI versus bacterial infection versus, because a lot of times the symptoms can overlap.
Kate RowlandHOST
Marks.
Kate RowlandHOST
I am often hesitant to recommend anything other than a very straightforward saline nose spray because of the issue that they had, I don't know, 10, 15, 20, I don't even remember how many years ago, With the Zycam nose swabs where people were doing, it was zinc, which does have maybe not amazing evidence, but maybe more than no evidence that zinc lozenges at least could have, or maybe it was some kind of oral zinc, could be protective against URI.
Kate RowlandHOST
Symptoms are short in the duration.
Kate RowlandHOST
So they had an intranasal preparation that they were selling for a while, but then they found that it caused irreversible anosmia.
Eli FreimanGUEST
Differential Diagnosis Now that you have completed your assessment, let's discuss a few of the common ailments causing cough that shouldn't be on your differential and how you might distinguish between them.
Eli FreimanGUEST
Upper respiratory infection, or URI, is one of the most common causes of cough in pediatric age groups.
Eli FreimanGUEST
On history, URIs present with cough, congestion, rhinorrhea, sore throat, and possibly fever.
Eli FreimanGUEST
Patients will often have been exposed to similarly sick contacts.
Eli FreimanGUEST
Time of year can also be an indicator as URIs are less common during the summer.
Eli FreimanGUEST
Exam will be negative for wheezing, crackles, stridor, or significantly increased work of breathing.
Eli FreimanGUEST
Diagnosis is clinical, or if influenza is suspected, a nasal pharyngeal swab can be done.
Walter DeHortyGUEST
And unfortunately, they're the ones that can die.
Sam MazurHOST
When do those kids generally present? Obviously, this is a long course that starts from what we would quote classic URI symptoms through this pretty persistent cough to getting better.
Sam MazurHOST
You know, from an epidemiological perspective, when do people tend to show up during this process of those three stages?
Walter DeHortyGUEST
Yeah.
Walter DeHortyGUEST
We don't want them to get pertussis during that time.
Sam MazurHOST
So I'm going to transition back to Percetussis, our wonderful patient.
Sam MazurHOST
And so we said, okay, babies can come in URI phase, whooping cough, or at least prolonged cough phase, followed by getting better.
Sam MazurHOST
Possibly if they're very young, they can have some apnea.