Trypanosoma brucei rhodesiense

Katie, can you break down the epidemiology

of Gambiense versus Rhodesiense hat?

Absolutely, Jess.

The vast majority, historically over 92 to 95 percent of all reported cases, is caused by Trypanosoma brucei Gambiense, endemic in 24 countries across West and Central Africa, with the Democratic Republic of the Congo accounting for over 70 percent of global cases.

Any day that we can avoid a lumbar puncture is a good one.

Let's move on to clinical management.

Lawrence and Katie, can you walk us through the brand new 2024 WHO treatment guidelines for both Gambiense and Rhodesiense hat?

Absolutely, yes.