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Troy T Rohn

Researcher

Aug 26, 2026

4:45
absolutely absolutely try so let's bring in the book here here we have got brain medicine so tell us a bit about you know for a common person how should they understand what this book is all about or is it only for a specific you know group of people try
5:06
Yeah.
5:08
Another great question.
5:09
And I have to tell you, it's really an interesting book in terms of how it was written because it's not a big read at all.
5:21
It has less than 150 pages and has over like 50 schematic diagrams, as I'm trying to explain the basic ABCs of gene therapy.
5:31
But Every chapter kind of begins with a personal anecdote of my own anxiety.
5:40
And so when I was pitching this idea to my book agent, She was like, well, who in the heck is going to read this book? Who's the audience for this book? Because, you know, it's not really a pure scholarly endeavor, but it's not a pure biographical, you know, story of my anxiety.

12 MINS LATER

17:45
How has that result been to understand it? Not it's the same thing, but just to understand the past form from the looking at towards the future.
3:45
absolutely absolutely try so let's bring in the book here here we have got brain medicine so tell us a bit about you know for a common person how should they understand what this book is all about or is it only for a specific you know group of people try
4:06
Yeah.
4:08
Another great question.
4:09
And I have to tell you, it's really an interesting book in terms of how it was written because, you know, it's not a big read at all.
4:21
It has less than 150 pages and has over like 50 schematic diagrams, you know, as I'm trying to explain the basic ABCs of gene therapy.
4:31
But Every chapter begins with a personal anecdote of my own anxiety.
4:39
When I was pitching this idea to my book agent, she was like, well, who in the heck is going to read this book? Who's the audience for this book? Because, you know, it's not really a pure scholarly endeavor, but it's not a pure biographical, you know, story of my anxiety.

10 MINS LATER

15:18
So does it ever occur to you that you are delving into an issue which you know which you also won't know how it will open up in the future it can be used well it can be misused it can not work out the way you envisage how about the gene therapy in other situations that has already been approved how has that result been to understand it not it's the same thing but just to understand the past form from the looking at towards the future
4:29
So from a neuroscience perspective, right, what actually is anxiety? Okay.
4:36
Yeah, so, I mean, anxiety is an adaptive response.
4:42
It's, you know, scientifically speaking, we need to have some anxiety because it allows us to adapt to and potentially, you know, escape a dangerous situation.
4:57
And the problem, though, is that if it becomes chronic... then it's not really serving any purpose.
5:06
So there are brain circuits in the brain that underlie this feeling.
5:13
It's really a fear response is what it is.
5:16
And it involves a structure in the brain called the amygdala.

6 MINS LATER

11:00
So where are we right now? You know, with this research, how close is it to becoming widely available?
speaker_0HOST
8:05
So I don't know if that kind of makes sense to you.
8:08
Yeah.
8:08
I mean, I think that makes total sense.
8:11
I think you framed it in the proper way.
8:16
It's really, again, a fear response that's stuck in overdrive.
8:21
It's a constant worry.
8:24
And it's not just psychological.

34 MINS LATER

speaker_0HOST
42:32
I'm looking for a question we've not answered yet.
6:47
How have your experiences with different treatments shaped the way that you think about these future therapies that we're gonna get into?
6:55
Yeah, again, I think it's just my own, my own experiences with my own anxiety and my background on neuroscience is that I feel like w- we can do better.
7:05
Just understanding that anxiety is really rooted...
7:09
It's n- I always say it's, it's not psychological, it's bio- biological.
7:14
So, you know, our anxiety is kind of rooted in our genes, it's rooted in the brain circuitry, and it's rooted in these chemical neurotransmitters.
7:23
And it's, uh, it's adaptive.
7:25
So when I think about anxiety, it's, it serves a purpose.

6 MINS LATER

13:35
That's amazing

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