transient cerebral isolation
71
MENTIONS
32
EPISODES
31
PODCASTS
Search complete. 71 mentions across 32 episodes found for "transient cerebral isolation".
Sep 11, 2026
Hanne ChristensenGUEST
we end up at having a recommendation, which is strong from ESO, that in minor stroke, which is very minor, NIH below or at three, or high-risk tier, dual antiplatelets with ACE and clopidogrel for 21 days is recommended if initiated within 24 hours of onset.
Hanne ChristensenGUEST
There's also a less strong recommendation for Ticagrelor and Acer to be used in mild to moderate stroke, that is going up to 5 in NIH and high-risk TIA, for 30 days, but it must also be initiated within 24 hours.
Hanne ChristensenGUEST
I think that...
Hanne ChristensenGUEST
Clopidogrel and Acer, the Clopidogrel and Acer option is what is really mostly used.
Joseph KwanGUEST
Unlike acute MI or ischemic heart disease, their relationship is very, very solid, even four or five decades ago.
Joseph KwanGUEST
But, you know, research in the last half of decades have really consolidated the place of LDL lowering in prevention of acute ischemic stroke.
Joseph KwanGUEST
So, for example, we have the SPARQL study that using atol for statin at 80 milligram for patients who have had a stroke, the number needs to treat to prevent one stroke or TIA was only 11.
Joseph KwanGUEST
And the number that needed to treat to prevent one major adverse cardiovascular event was only five.
David AirdrieHOST
I'm David Airdrie, Executive Director of Thrombosis Canada, and I'm joined again by my co-host, Dr. Maha Osman from Queen's University in Kingston, and Dr. Jamil Abdul-Rayman from Toronto General Hospital.
David AirdrieHOST
Today, we're discussing oceanic stroke, a large phase three randomized trial examining asindexin, an oral factor 11A inhibitor for secondary prevention after non-cardioembolic ischemic stroke or high-risk TIA.
David AirdrieHOST
The study enrolled more than 12,000 patients and was published in the New England Journal of Medicine.
David AirdrieHOST
We're very pleased to welcome the study's principal investigator and first author, Dr. Mike Sharma.
8 MINS LATER
Mike SharmaGUEST
We just didn't have the infrastructure.
Mike SharmaGUEST
But this went very quickly, indicating both that these patients are common, and secondly, that investigators really have a question.
Mike SharmaGUEST
And just to let you know how people got in, you had to be within 72 hours of symptom onset, either a stroke or a TIA, which was high-risk.
Mike SharmaGUEST
And at that point, you didn't have a known high-risk cardioembolic source.
Diane CarboHOST
So I pushed her over and we drove right to the hospital.
Diane CarboHOST
She had TIAs before, mini strokes or early signs of a future stroke.
Diane CarboHOST
And I took her.
Diane CarboHOST
And when I was there, I was just a friend.
Blanche d'AlpugetGUEST
Um, and then he had two small, little strokes.
Blanche d'AlpugetGUEST
They're called transient ischemic attacks, I think, TIAs.
Blanche d'AlpugetGUEST
And, and then he had a, a large stroke, a, I mean, a real stroke, and that left him, uh, his, the right side of his body very weak, and he, and he had to learn to talk again properly.
Blanche d'AlpugetGUEST
My son made a very good suggestion to him.
Christy Byrne YatesGUEST
He had had a stroke.
Christy Byrne YatesGUEST
He had some mini TIAs, and he took a lot of different medication.
Christy Byrne YatesGUEST
And my mom would go and fix his medication, [laughs] pills, you know?
Elizabeth MillerHOST
Okay.
HeatherHOST
You mentioned that you had had strokes before.
HeatherHOST
As I understand it, these were not TIAs.
HeatherHOST
They were full strokes.
HeatherHOST
Is that correct?
David HaleGUEST
They just know that they're feeling some quarter, some, some sort of dizziness, and they don't feel well right now.
David HaleGUEST
Um, so whenever someone is in that episodic bucket, the other, uh, categories of disease that you don't wanna overlook especially is a transient ischemic attack, a TIA.
David HaleGUEST
Um, that's going to be something that is spontaneous and episodic without a warning sign often.
David HaleGUEST
And then more common spontaneous causes of dizziness, though would expect it to be slightly longer, would be things like vestibular migraine or Meniere's disease.
David HaleGUEST
When you're thinking about something like TIA, vestibular migraine, or Meniere's disease, a lot of the times you have to really ask the patient what the associated symptoms are.
David HaleGUEST
Um, and that's how you're going to help differentiate.
David HaleGUEST
You know, for the TIA, you're asking about any other neurologic symptoms that happened at the same time of the event, though isolated dizziness is a possibility to, um, present as a TIA.
David HaleGUEST
And for your patients with vestibular migraine, it's the same types of questions you'd be asking in your headaches, uh, review of systems, like light or sound sensitivity and a description of that patient's headache, visual aura.
CharlieHOST
Now, Bernie ended up with one more legal battle in prison, and in this one, he was the plaintiff, and he was also, in my opinion, clearly in the right.
CharlieHOST
In 2023, after being housed in a cell with no air conditioning and temperatures hitting 110 degrees, Bernie had a transient ischemic attack, or a TIA, aka a mini-stroke.
CharlieHOST
So he sued the prison system.
CharlieHOST
Others joined the suit in a class action, which was helpful because it meant that the state had to fix it for everyone, not just Bernie.
Kristen DilleyHOST
Having a TIA is not a joke.
Kristen DilleyHOST
I've had family members and loved ones with TIAs before.
Kristen DilleyHOST
It is scary stuff, and it can come on due to high stress.
Kristen DilleyHOST
And then a couple of years after that first TIA, about a year and a half later, a jailhouse letter arrived from an inmate who had learned about Kate's case through the newspaper and was attempting to extort money from Lois.
Kaylee HayesGUEST
So it causes inflammation within the brain.
Kaylee HayesGUEST
And we know that increases the risk of strokes, and kind of those mini strokes called TIAs.
Kaylee HayesGUEST
And so there might be a thought that by reducing those, even ones that might not really come to clinical attention, we don't notice them, and reducing any inflammation that's happening that we also might not notice, as well as, you know, the horrible cases of shingles, there might be actually that preservation of brain function.
Vassy KapelosHOST
Okay, that's very helpful.
22 more episodes mention transient cerebral isolation.
Create an account to see the whole feed, search across every transcript, and follow the entities you care about.