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toxic diffuse goiter

toxic diffuse goiter

DiseaseWikipedia

Search complete. 94 mentions across 20 episodes found for "toxic diffuse goiter".

Oct 30, 2026

Christos MantzorosGUEST
0:52
Thank you, Laura.
Christos MantzorosGUEST
0:53
It's a pleasure to be here at Beth Israel Deaconess Medical Center, where our lab is, and to discuss this important condition, historically known as Graves' ophthalmopathy.
Christos MantzorosGUEST
1:07
Thyroid eye disease is a useful example of how endocrine autoimmunity can affect organs well beyond the thyroid gland.
Christos MantzorosGUEST
1:20
It is also really timely to talk about it now because based on discoveries at the basic research field, we are having more and better medications and diagnostics.
Laura ValenzuelaHOST
2:42
Manzoros, what is your differential diagnosis and how do you connect her thyroid findings and her eye manifestations?
Christos MantzorosGUEST
2:50
Yes, Laura.
Christos MantzorosGUEST
2:51
I think this is a classic presentation of Graves hyperthyroidism with thyroid eye disease.
Christos MantzorosGUEST
2:58
So, we have suppressed TSH, elevated thyroid hormones, and positive TSH receptor antibodies, all of which support Graves' disease.
Kimberly CockrumHOST
12:41
So let's start with case one.
Kimberly CockrumHOST
12:42
So a 72-year-old woman with Graves disease for six years had been previously treated with radioactive iodine and oral steroids.
Kimberly CockrumHOST
12:51
She became hypothyroid and developed eye symptoms.
Kimberly CockrumHOST
12:54
Her eye symptoms included intermittent and worsening diplopia, eyelid, and ocular swelling and redness.

8 MINS LATER

Kimberly CockrumHOST
21:26
Again, we're looking at how to optimize patient outcomes and experience in light of the changing landscape in thyroid eye disease.
Kimberly CockrumHOST
21:34
So here's our next patient.
Kimberly CockrumHOST
21:35
52-year-old woman presents with Graves' disease.
Kimberly CockrumHOST
21:38
She was diagnosed in 2015.
Eric BergHOST
5:19
So selenium helps you make glutathione that helps you deal with this hydrogen peroxide, which can create a toxicity in your thyroid.
Eric BergHOST
5:28
Also, when you get Graves' disease, which is a hyperthyroid problem, a lot of times you get these bulging eyes well selenium helps reduce that symptom too now where do you get selenium well it's in meat it's in fish it's in eggs it's in dairy cruciferous vegetables like cabbage and broccoli it's in nuts it's in onions it's in garlic and it's definitely in organ meats selenium can also help decrease the risk of getting those thyroid nodules.
Eric BergHOST
5:56
And it can even help prevent the enlargement of your thyroid.
Eric BergHOST
5:59
And your thyroid has other mechanisms of accumulating selenium, helping recycling it, and making sure that you're not ending up in a low selenium situation.
Angela MazzaGUEST
41:22
And what we're seeing too is patients with Hashimoto thyroid is who we're just checking the And I'm not saying we have to do this for everyone.
Angela MazzaGUEST
41:29
Hashimoto thyroiditis swinging into Graves' disease with those thyroid antibodies.
Angela MazzaGUEST
41:35
And that really was unheard of up until maybe less than 10 years ago.
Angela MazzaGUEST
41:42
It was always Graves swung into Hashimoto's, but now we're seeing more and more cases of Hashimoto's swinging into Graves'.
Angela MazzaGUEST
41:48
Which is an overactive autoimmune thyroid.
Steve HoffartHOST
41:51
Yeah.
LiuHOST
15:00
And that's when you're making too much thyroid hormone.
LiuHOST
15:03
That's called Graves' disease.
LiuHOST
15:05
Because too much iodine can cause a direct oxidative stress damage to thyroid cells themselves.
LiuHOST
15:12
And it causes them to enlarge into a giant quarter.
A.P. MartinHOST
11:28
One of them is low and the other is high.
A.P. MartinHOST
11:31
Graves is high.
A.P. MartinHOST
11:34
And with Graves, your eyes can be bulging out.
A.P. MartinHOST
11:38
You can have a tremor.
A.P. MartinHOST
11:40
Your thyroid, think of it, is your gas pedal in your car.
A.P. MartinHOST
12:06
And the opposite of that is Hashimoto's.
A.P. MartinHOST
12:11
which is an autoimmune thyroid condition where you're into real low functioning thyroid.
A.P. MartinHOST
12:20
The vast majority of people that have trouble with their thyroid neither have hyper nor like they don't have Graves and they don't have Hashimoto's, but their thyroid's not working properly.
Eric OsanskyHOST
0:31
Thank you for joining me on a Save My Thyroid podcast, where I help people save their thyroid and regain their health.
Eric OsanskyHOST
0:37
My name is Dr. Eric Osansky, and if you have hyperthyroidism, including Graves' disease or toxic multinodular goiter, then you will especially benefit from these episodes.
Eric OsanskyHOST
0:47
If you have Hashimoto's thyroiditis, you also need to save your thyroid, and therefore you'll also find many of the episodes to be valuable, including this one, as in this episode I discuss how the autoimmune component of Graves' disease and Hashimoto's can have a negative effect on bone health, even if someone has an optimal thyroid panel.
Eric OsanskyHOST
1:05
In a past episode, I've discussed the impact of thyroid imbalances, especially hyperthyroidism on bone health, but the immune system can also play a role in the development of osteopenia and osteoporosis, which is yet another reason why you don't want to ignore elevated thyroid antibodies.
Eric OsanskyHOST
1:23
As usual, make sure you listen to the post-episode chat after the outro music as I'll expand on three reasons to pay attention to elevated thyroid antibodies, pros and cons of taking medication for osteoporosis, vitamin D and other bone-building nutrients, and when should you get a DEXA scan.
speaker_1NARRATOR
2:12
The following discussion is for educational purposes only and is not intended to diagnose or treat any disease.
speaker_1NARRATOR
2:18
Please do not apply any of this information without first speaking with your doctor or Now let's head to the show.
Eric OsanskyHOST
2:30
Most people tuning into this know that I personally dealt with Graves' disease and restored my health.
Lisa PratherHOST
44:54
And Dr. Prather, let's talk about your personal history with chiropractic.
Robert PratherHOST
44:58
I had developed Graves' disease,
Lisa PratherHOST
45:00
which is an
Robert PratherHOST
45:02
autoimmune hyperthyroid.
Robert PratherHOST
46:14
But the chiropractic adjustment for the atlas was the single most important thing for my healing.
speaker_2UNKNOWN
46:21
Mm-hmm.
Lisa PratherHOST
46:22
And you do not have Graves' disease anymore.
Robert PratherHOST
46:24
I do not have Graves' disease anymore.
Mindy PelzHOST
1:05
First toxin, mercury.
Mindy PelzHOST
1:07
So there is research showing that mercury toxicity has been linked to thyroid problems, specifically Hashimoto's and Graves.
Mindy PelzHOST
1:16
It has also been linked to RA, and it has been linked to chronic fatigue syndrome, which isn't necessarily an autoimmune condition, but it has autoimmune type symptoms.
Mindy PelzHOST
1:27
So we'll talk about that in a moment.
Mindy PelzHOST
1:29
Let's start with Hashimoto's and Graves.
Mindy PelzHOST
1:31
The thing to understand about Mercury is that it is sitting in the receptor sites for things like selenium and iodine.
Mindy PelzHOST
1:40
So a lot of times when it sits in those receptor sites in the thyroid, all of a sudden now your body starts to attack itself.
Lauren PapanosHOST
16:21
Let's talk about the thyroid.
Lauren PapanosHOST
16:22
So the thyroid, interestingly, with hyperthyroidism, where you have high levels of T3 and T4 and low levels of TSH, especially with Graves', where there's also the presence of thyroid antibodies, this is actually associated with low neutrophils.
Lauren PapanosHOST
16:37
And there's also typically this triad that we see.
Lauren PapanosHOST
16:40
It's called the Kocher triad, and it's this triad where there's low white blood cells alongside of low l- neutrophils and a higher percentage of lymphocytes, and that's something that's classically seen with Graves'.
Lauren PapanosHOST
16:51
On the reverse side of the spectrum with hypothyroidism, it's interesting because we almost see the exact same pattern happen within the immune system.
Lauren PapanosHOST
16:58
So although they're, like, completely different thyroid pictures, how the immune system is getting affected is very similar.

10 more episodes mention toxic diffuse goiter.

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