(S)-(−)-timolol
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Search complete. 5 mentions across 5 episodes found for "(S)-(−)-timolol".
Nov 1, 2026
Andrew WhiteGUEST
We understand it was largely born out of that.
Andrew WhiteGUEST
The first blockbuster eyedrop was Timolol in the 1970s.
Andrew WhiteGUEST
And that's the first one that actually worked, but it still didn't work that great.
Andrew WhiteGUEST
And because of systemic side effects like causing asthma and bradycardia and stuff, it wasn't for everybody.
Richard Schulze JrGUEST
And you know, early in my career, my dad and I did a lot of trabeculectomies.
Richard Schulze JrGUEST
Of course, in his era, what did they have? They had Timolol and pilocarpine.
Uday DevganHOST
Right.
Richard Schulze JrGUEST
And beyond that, all right, well, let's do a Trab.
Ahmad Mohammed SaboGUEST
Uh, they may also use some, uh, uh, adrenergic drugs that could really interfere with the way the eye operates and to decrease pressure and allow...
Ahmad Mohammed SaboGUEST
A lot of people know about Timolol and the rest, and the rest that are commonly used.
Ahmad Mohammed SaboGUEST
Uh, this is not the right place to talk about the specific drugs.
Lukman Awol AgunuHOST
Okay.
Abdelrahman ElhusseinyGUEST
About half of the patients in the carbonic anhydrase group were on prostaglandin analog, about 40% were on beta blockers, and about 30% was alpha-2 agonist.
Abdelrahman ElhusseinyGUEST
It was important that we match and control for all of those medications, specifically Bermanidine and Timolol, because those have been associated with some neuropsychiatric signals in previous studies as well.
Abdelrahman ElhusseinyGUEST
In addition to that, we adjusted also for the number of glaucoma surgeries, cataract surgeries that both groups had.
Drew CareyHOST
And tell us, what did you find with regards to depression, anxiety, and initiation of antidepressant medications after patients were started on the topical carbanic anhydrase inhibitors compared to your control group?