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Thioridazine

Thioridazine

Search complete. 14 mentions across 5 episodes found for "Thioridazine".

Oct 22, 2026

Justin GarsonGUEST
8:11
The main thing that happened in the mid-'80s when he was put on this combination of drugs, one of them was one of the first generation antipsychotic drugs.
Justin GarsonGUEST
8:20
It was called Melaril.
Justin GarsonGUEST
8:23
And the other was lithium, a mood stabilizer.
Justin GarsonGUEST
8:26
And we now know that this combination is neurotoxic.
Cody ArmstrongHOST
19:45
So we don't have a lot that are available as long-acting injectables, and this is one of them, so it does have some use still.
Cody ArmstrongHOST
19:53
Our next medication, thioridazine, um, brand name Mellaril, I do not think this is available anymore.
Cody ArmstrongHOST
20:01
It came out in 1962.
Cody ArmstrongHOST
20:04
I have actually used it.
Cody ArmstrongHOST
20:08
It was, it was a prison population.
Cody ArmstrongHOST
20:11
While I was in med school, I had a, uh, it was, it was a prisoner in our hospital, uh, that was, you know, sent from the prison to our hospital, and I can't actually say I used it.
Cody ArmstrongHOST
20:24
He was on Mellaril, and he had to be taken off to treat an illness because the, the medication that they were using to treat his illness lowered blood pressure and Mellaril lowers blood pressure, so they said they couldn't use it at the same time.
Cody ArmstrongHOST
20:37
So they're actually consulting us to see what could we use instead of Mellaril and he really wanted his Mellaril.
FuHOST
71:07
Okay.
FuHOST
71:07
Anyway, um, next we are labeling this as perphenazine, AKA Trilafon, but I want you to also think of thioridazine, Mellaril, and trifluoperazine, Stelazine.
FuHOST
71:19
These are kinda the miscellaneous first generations that got forgotten.
FuHOST
71:23
You might not even be able to get it in your area depending on where you are.
Ioannis SkiotesGUEST
4:31
And then, you know, sometimes I was hallucinating in there, and you're seeing things and seeing demons, and it wa- it was, you know, it was a horrific experience.
Ioannis SkiotesGUEST
4:41
And one caused my heart arrhythmia, a drug called Mellaril.
Ioannis SkiotesGUEST
4:46
And, uh, so I had AFib, I carried AFib for 37 years, and because I have good health insurance now I was able to get a heart ablation and get rid of it, but I could have died.
Ioannis SkiotesGUEST
4:59
And eventually that drug was taken off the market because it caused AFib, and so they got rid of Mellaril.
Ioannis SkiotesGUEST
5:07
But during my time in there in '79 and 80 to '81, um, they had it and they, they...
Ioannis SkiotesGUEST
5:14
That was one of the drugs they fed me.
Ken BerryHOST
5:55
Also, metformin or Glucophage lowers your CoQ10 levels as well.
Ken BerryHOST
6:00
Next is any, many of the antipsychotic medications like Haldol or Mellaril, they can just wreak havoc on your CoQ10 levels.
Ken BerryHOST
6:10
Doesn't mean stop taking them, it means do the following.
Ken BerryHOST
6:13
So if you're taking one or two or three or four of the medications in the list down below, you're destroying your body's levels of CoQ10 and you're hampering your body's ability to be as energetic, as energized as it could be otherwise.

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