The Methodist Hospital
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Search complete. 2 mentions across 1 episode found for "The Methodist Hospital".
Oct 8, 2026
Targeting Immune Dysfunction in ALS
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6:11Arun SwaminathanGUEST
We stand on the shoulders of some scientific giants.
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6:14Arun SwaminathanGUEST
One is Dr. Stanley Apell at Houston Methodist, who made the connection among other people as well, but he made the connection between dysfunctional T regs and the progression of neurodegenerative diseases And the, and the correlation is pretty strong, Danny.
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6:33Arun SwaminathanGUEST
The correlation between dysfunctional Treg and ALS is pretty good.
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6:39Arun SwaminathanGUEST
If you look at ALS patients, their Tregs are highly dysfunctional, and dysfunctional Tregs are a good predictor of ALS progression as well.
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6:47Arun SwaminathanGUEST
So this was all a lot of the work done by Dr. Stan Appell at Houston Methodist, and of course, many others as well.
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6:55Arun SwaminathanGUEST
But if you go back a little bit, a decade, uh, then Dr. Appell's been working on this with neuroinflammation being the driver of these diseases for decades.
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7:06Arun SwaminathanGUEST
And I think finally, he and many others who have been screaming that from the rooftop are getting validated.