The Journal of Physiology

And increasingly, we're discovering that mitochondrial function itself is temporally organized.

A 2025 review in the Journal of Physiology specifically examined the relationship between the skeletal muscle circadian clock and mitochondrial dynamics.

And one of the key players is BMAL1, and that's an acronym, capital B-M-A-L-1, which is one of the major molecular clock proteins.

And disruption of this clock machinery has been associated with changes in mitochondrial dynamics, metabolic dysfunction, insulin resistance, and deterioration of skeletal muscle function.

And also he's gonna be sharing some brand new data that was just published that his team was actually involved in as well.

And this incredible paper was published in the Journal of Physiology.

And it's gonna be talking about some incredible science demonstrating how you can improve your stamina, how you can improve your recovery, how you can improve your overall feeling of energy, again, backed by science.

And so all of this and so much more in this powerful new interview with the amazing Dr. Latt Mansor.

And you and your team were actually involved in a really fascinating study that just came out this year.

And this study was looking at the relationship between ketosis, exercise, and vascular function.

And as everybody can see, we put the study up, it's published in the Journal of Physiology.

and there were some incredible findings.

One was a very simple sort of over-training study where we really stressed these mice, and those that got the nandrolone, to no surprise, handled the stress better.

The more interesting thing is probably the muscle memory effect, whereas I think you go back all the way to 2001, I think it's a Journal of Physiology paper in 2001.

They had pellets.

They did testosterone pellets in the mice versus not, and they had them on the, the testo and then, and then they dropped it off and then they, they aged them for I think six weeks, something along those lines, but they aged them for a period of time.

Moderate evidence.

Carbohydrate feeding rapidly restores liver glycogen within six hours after exhaustive exercise, but muscle glycogen requires nearly 24 hours for complete recovery, according to a new study published in the Journal of Physiology.

The research reveals fundamental differences in how the body's two main glycogen stores respond to post-exercise nutrition, with important implications for athletes planning recovery protocols.

Key Takeaways Liver glycogen fell 34% during exhaustive cycling but fully recovered within 6 hours of carbohydrate feeding.

Muscle at 12 of 70% without carbs, 12H.

Depleted source.

The Journal of Physiology, 2024.

Georgian Medical Journal News.

Human research has also shown that physical movement and breathing can influence lymphatic circulation.

A study published in the Journal of Physiology examined how skeletal muscle contractions affected the clearance of tracer material from muscle tissue.

Researchers observed increased local tracer clearance during muscle contractions compared with resting conditions.

Human research has also shown that physical activity can influence lymphatic circulation.

The other says it's intensity, that they say how hard you go matters more than how long.

And it's even got a name in the Journal of Physiology.

It's called the mitochondrial content contest.

So let's dig into this study.

Editorially reviewed by Prof. Giorgi Picadze, MD, MPH, PhD, GMJ News Desk.

Moderate evidence when athletes consume carbohydrates after exercise matters significantly for muscle recovery, according to recent research published in the Journal of Physiology and Journal of Applied Physiology.

Even when total daily carbohydrate intake is identical, the first few hours after exercise create a metabolic window where nutrient timing produces measurably different muscle adaptation outcomes compared to delayed consumption.

Key Takeaways Post-exercise carbohydrate timing significantly affects muscle recovery, independent of total daily carbohydrate volume.

Muscle glycogen resynthesis rates by intake timing independent of total daily carbohydrate volume.

Immediate post-exercise, 0-2 hours, 95%, 2-4 hours post-exercise, 78%, 4-8 hours post-exercise, 62%, delayed, 8 plus hours, 38%.

Research from Fuchs and colleagues published in the Journal of Physiology demonstrates that muscle cells exhibit heightened glucose transporter activity and glycogen synthesis rates immediately after exercise cessation.

This metabolic state persists most robustly during the first 2-4 hours, during which muscle tissue is primed for rapid carbohydrate uptake and storage.

A major reason for this is that Noble doesn't publish in journals that specialize in evolutionary biology.

He publishes his ideas on evolution in the Journal of Physiology, or the Journal of Experimental Biology, or often the journal that he was the editor-in-chief of for many years, Progress in Biophysics and Molecular Biology.

Under Noble's editorship, this journal rapidly became a crackpot journal, publishing papers like Cause of Cambrian Explosion, Terrestrial or Cosmic, in which the authors claimed that octopuses came from outer space.

It has also published a series of papers by a pair of creationists, Olin Brown and Dave Hollander, with titles like, Neodarwinism Must Mutate to Survive, and Darwinian Evolution Has Become Dogma, AI Can Rescue What Is Salvageable.