Th22 cell

IL-6, TNF, but that drives this inflammatory cascade that keeps going on.

So once that happens, they present these to the body's immune system, and they first present it to naive T cells, and then these naive T cells differentiate into Th1, Th17, and Th22 subsets.

So now we have Th1, Th17, and Th72 subsets of T cells, and they continue this inflammatory cascade and it turns into a vicious cycle.

Devin, once these T-cell subsets are formed, how do they get back into the skin and drive plaque formation?

And then this new complex, this new part of the keratinocyte and part of this antimicrobial peptide, which has now come together as a new entity, is picked up by dendritic cells.

And then you have this basically immune response to this new complex.

And that's where you're talking about interferon-alpha, coming down with now IL-1, which is, you know, a primary inflammatory cytokine, IL-6, TNF, and then that basically initiates a T cell response with some of the more familiar T cells, Th1, Th17, Th22.

Is that what's happening? Exactly.