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TBC1D1
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MENTIONS
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Search complete. 1 mention across 1 episode found for "TBC1D1".
Oct 8, 2026
How Much Lifting is Enough? How Much is Too Much?
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62:20Jordan FeigenbaumHOST
And that all activates AMP kinase, which is the cell's energy sensor.
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62:24Jordan FeigenbaumHOST
AMP kinase, like kinases do, phosphorylates TBC1D1, the sister protein to TBC1D4, and it releases a different break on the same vesicles storing GLUT4, which again end up on the surface of the cell and sugar can come in.
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62:40Jordan FeigenbaumHOST
But this one needs no insulin at all.
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62:43Jordan FeigenbaumHOST
The persistence of the effect is related to TBC1D4, which carries phosphorylation sites for both AKT and AMP kinase, and it responds on a delay.