Yeah, yeah.

It's the fact that there's an irreversible component to this disease.

It shouldn't be save your best for last.

It should be understanding where are they today? Are they progressing? Or do I believe that they're progressing because of X, Y, Z factors? Let me get at them on the best drug so that they can have resolved kind of symptomology, whether that's the abscesses, nodules or tunnels.

And the hope is that that is then helping with preventing the progression of the disease.

So I think we're not quite there yet.

That's where we'd like to go.

What is getting away? Is it the evidence, guidelines, payer restrictions, clinician comfort, patient concerns, just therapeutic inertia or just not seeing the forest from the trees? Because I have my own thoughts on it, but I'd love to hear the perspective coming from industry of why is this still a problem?