Tamoxifen
DrugWikipedia
29
MENTIONS
23
EPISODES
21
PODCASTS
Search complete. 29 mentions across 23 episodes found for "Tamoxifen".
Sep 15, 2026
Avanti Kumar SinghHOST
Mm-hmm.
Elise LoehnenGUEST
But I would've been put on, not Tamoxifen because of my brain aneurysm.
Elise LoehnenGUEST
I would've been put on Lupron, which would've put me-
Avanti Kumar SinghHOST
Mm-hmm
Scott McNallyHOST
56 boxes of
Dave CroslandHOST
Tamoxifen, 44 boxes of Tamoxifen, 241 Klen, 260 Klen.
Scott McNallyHOST
It's that
Dave CroslandHOST
much? 32 clen, 49 clomid, 50 clomid.
SteveHOST
Uh, so I, I suspect water retention.
SteveHOST
If you're really worried, throw in Roloxifene or Novadex or buy some DHT.
SteveHOST
I mean, my skin at my chest was the thinnest when I was on DHT and Enanthate.
SteveHOST
Um, so now gain- I gained a little bit back, and then when I go on DHT Enanthate, I'm sure it will come down a little bit leaner again.
Lau SuyinGUEST
But there are some medications that can increase the risk of fatty livers.
Lau SuyinGUEST
For example, tamoxifen, steroids.
Lau SuyinGUEST
Tamoxifen
Ida Normiha HilmiGUEST
is usually used.
Ida Normiha HilmiGUEST
I don't know whether it's used more.
Jill CarnahanHOST
Yeah.
Meenal AgarwalGUEST
You know, there's Tamoxifen, a very popular drug for breast cancer, that it deposits in our retina as well.
Meenal AgarwalGUEST
So there's a lot of, you know, retinal changes that can happen-
Jill CarnahanHOST
Oh
Jillian GoddardHOST
The recommendation is that if you have zero risk factors for osteoporosis, you can have your first bone density at age 65. but if you have risk factors which includes if you have a mother or sister who had a fracture if you yourself have fractured a bone during adulthood and a bunch of other factors you should actually have a bone density test at menopause so quite a bit
Erin SteinHOST
As I've said before, I already got one because my mother does have some of these concerns and I was starting Tamoxifen and I just wanted to get a baseline and I had no problem getting a bone scan just to see where I was starting from.
Erin SteinHOST
so that I can keep an eye on it going forward.
Erin SteinHOST
So if you feel like it runs in your family, you have other risk factors, or you're going on medication that might affect your bones, get it earlier.
Nyjon EcclesGUEST
yes
Alex SimmsHOST
And then I went down that whole thing of having Tamoxifen and having really chronic symptoms from, you know, perimenopause and all of that.
Alex SimmsHOST
And I only lasted two years on Tamoxifen before my oncologist said, your quality of life is more important.
Alex SimmsHOST
We're going to let you go back on HRT.
Alex SimmsHOST
But lots of people said to me, you need to be going on bioidentical HRT.
Neil LoveHOST
She had decisions made prior, I guess, to Reshma Sinha not to give any kind of anti-HER2 therapy or chemo.
Neil LoveHOST
She was on Tamoxifen for five years, then presented to the ER, short of breath, with a pericardial fusion with emerging tamponade.
Neil LoveHOST
They found she had, obviously, a malignant effusion.
Neil LoveHOST
She is currently, I guess, on TDXD and pertuzumab.
Amanda ButlerGUEST
Yeah, I did Lupron.
Amanda ButlerGUEST
I'm on Tamoxifen now.
Amanda ButlerGUEST
Tamoxifen now, okay.
Amanda ButlerGUEST
Yes, for five years.
Amanda ButlerGUEST
For five years, wow.
Celine PrellHOST
A patient with a history of estrogen receptor positive breast cancer has been stable on tamoxifen for years.
Celine PrellHOST
They were started on bupropion for depression and later experienced a recurrence of their cancer.
Celine PrellHOST
Could a medication interaction have contributed? Tamoxifen is a prodrug that needs CYP2D6 to convert it into its active metabolite, endoxifen.
Celine PrellHOST
Bupropion significantly inhibits 2D6, so it can reduce the amount of active endoxifen that's produced and potentially reduce the effectiveness of tamoxifen.
Celine PrellHOST
So in a patient taking tamoxifen, we generally try to avoid strong 2D6 inhibitors like bupropion or paroxetine when alternatives are available.
13 more episodes mention Tamoxifen.
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