Susan Redline

So polysomnography or sleep as defined primarily by electroencephalogram is considered our gold standard for objective sleep measurement.

Um, but what Susan Redline once told me, she said, "You know, it's more like a bronze standard." And the reason that is, it's im- it's imperfect, and how do we know something is an imperfect measurement when it's considered the gold standard, and it's the most in-depth measurement objectively that we currently have? The way we know it's uncertain is because of something called inter-rater reliability, that when you have two or more experts and they are asked to rate an epoch, to stage an epoch, we oftentimes will not have perfect agreement, and it's in the mid-eighty percentiles around.

And so why is that? If this is our best way to measure sleep, why is it imperfect? Why is there this inherent uncertainty? And there's a few reasons that have been cited which I think are fascinating.

And one of them, and I don't know who coined this, so if someone can put it in the comments, is that the process of annotating or staging sleep, uh, is discretizing the continuum.

But this is the first time on the main stage at Sleep.

with Susan Redline and um Dennis Wang which was a really big honor and yeah

what was your main message with with that is the struggles you went through and so they could

hear no so it was very very focused on the current um issue with more and more treatment options becoming available and how patients can access them so um I've actually got it here not that I walk around with it But the overall, the title for our whole, the three of us was Bridging Evidence and Experience, Clinical Outcomes and Patient-Defined Value in OSA Therapy.