
Sirtuin
2
MENTIONS
1
EPISODES
1
PODCASTS
Search complete. 2 mentions across 1 episode found for "Sirtuin".
Aug 24, 2026
“Age Reversal Is Coming.” Inside The First Human Trials - Dr David Sinclair - #1141
D
38:37David SinclairGUEST
Um, also eating plants that are stressed is a sign to your body that your food might run out.
D
38:41David SinclairGUEST
This is put your body in adversity mode, and this enzyme that I mentioned earlier called Sirtuin, which protects the epigenome, it responds to hunger and exercise.
D
38:50David SinclairGUEST
Um, there's a molecule called NAD that a lot of your listeners and viewers would know about.
D
38:55David SinclairGUEST
This enzyme responds to NAD levels.
35 MINS LATER
D
74:00David SinclairGUEST
That's a low dose.
D
74:02David SinclairGUEST
It's just, uh, a, a little bit.
D
74:05David SinclairGUEST
And I, I do that because in 2012, we published a paper that showed that one of the, the most pernicious causes of aging is low blood flow, and that we could reverse that with NMN through Sirtuin, more blood flow.
D
74:22David SinclairGUEST
And it's really underappreciated how much a lack of blood flow leads to diseases, your... especially your, your muscles and your brain.