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Sirtuin

Sirtuin

Search complete. 2 mentions across 1 episode found for "Sirtuin".

Aug 24, 2026

David SinclairGUEST
38:37
Um, also eating plants that are stressed is a sign to your body that your food might run out.
David SinclairGUEST
38:41
This is put your body in adversity mode, and this enzyme that I mentioned earlier called Sirtuin, which protects the epigenome, it responds to hunger and exercise.
David SinclairGUEST
38:50
Um, there's a molecule called NAD that a lot of your listeners and viewers would know about.
David SinclairGUEST
38:55
This enzyme responds to NAD levels.

35 MINS LATER

David SinclairGUEST
74:00
That's a low dose.
David SinclairGUEST
74:02
It's just, uh, a, a little bit.
David SinclairGUEST
74:05
And I, I do that because in 2012, we published a paper that showed that one of the, the most pernicious causes of aging is low blood flow, and that we could reverse that with NMN through Sirtuin, more blood flow.
David SinclairGUEST
74:22
And it's really underappreciated how much a lack of blood flow leads to diseases, your... especially your, your muscles and your brain.

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