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Sara Y Oikawa
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Aug 24, 2026
The Science of Losing Fat Without Losing Muscle: Dr. Sara Oikawa
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9:02Vanessa SpinaHOST
So can you walk us through the design, the population, what the protocol was, and what you were trying to understand?

Sara OikawaGUEST
So kind of walking us through the design, it-- the goal of the study was un- to understand what happens to skeletal muscle metabolism and skeletal muscle mass when we have people go through these periods of simulated convalescence.

Sara OikawaGUEST
And so in plainer terms, what happens when, you know, you have a two-week period of your life where you're really limited in what you can do.

Sara OikawaGUEST
I do a lot of more work now in, in surgery, and so I'm seeing that firsthand and then probably TMI for everyone listening to your podcast [chuckles], but a couple weeks ago, actually, I had shingles, and I had this exact same experience, which is ultimately where, you know, you go through a period of time where your physical activity is pretty limited.

Sara OikawaGUEST
And when I say limited, I mean very drastically limited, right? You're not feeling well, and this could result from a bunch of things.
28 MINS LATER
V
37:48Vanessa SpinaHOST
Can you walk us through some of the research you've done there and what you were specifically wanting to test?