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Safrole

CompoundWikipedia

Search complete. 8 mentions across 3 episodes found for "Safrole".

Sep 24, 2026

KarenHOST
11:49
And then the ethers, myristicin, This one from Indonesia almost has 11%, and we're gonna find out what this means.
KarenHOST
11:59
And saffrol, 1.75%, which isn't very much, but it's the ethers in nutmeg that brings us our safety information.
KarenHOST
12:13
What we look at is determine how much nutmeg we can use in a blend is from the ethers, and this will greatly vary depending on what country.
KarenHOST
12:25
Now, as I say that, sometimes it doesn't matter which country it is.

6 MINS LATER

KarenHOST
19:00
And nano means it was small amounts.
KarenHOST
19:02
Okay, so they used a small amount in the small areas.
KarenHOST
19:07
And the second thing, so that one, that saffrol is connected to our link down below from NCBI.
KarenHOST
19:17
Now, saffrol, it's a major component of sassafras oil.
Simon DohertyHOST
15:07
on drugs caused all this.
Simon DohertyHOST
15:08
The situation came about as a result of the UN banning a precursor to MDMA, Saffrol, in 1988.
Simon DohertyHOST
15:16
Then, over the next couple of decades, they staged a large crackdown on the trade of it.
Simon DohertyHOST
15:22
In the late 2000s, it all came to a head.
Simon DohertyHOST
15:31
It was enough to make 250 million pills and it created a monumental drought.
Simon DohertyHOST
15:37
This did significantly dent availability for MDMA production, according to drug science, so chemists looked for an alternative source of a suitable precursor.
Simon DohertyHOST
15:48
Aniseed oil seemed like the ideal alternative as it was chemically very similar to Saffrol, so this was used.
Simon DohertyHOST
15:55
Unfortunately, the product that results from using the MDMA production process with aniseed oil is PMA or PMMA.
WilliamHOST
12:21
As food science developed, researchers began taking a much closer look at the chemicals naturally occurring in plants.
KatHOST
12:29
Saffrol eventually became the subject of safety concerns, particularly after studies raised questions about its potential health effects.
KatHOST
12:37
That created a major problem for manufacturers.
KatHOST
12:41
How do you keep the familiar flavor people expect from root beer while removing an ingredient that regulators no longer consider safe for use in food? The answer was reformulation.

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