
Read Montague
American neuroscientist
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Jul 6, 2026
Ep161 "What Do Ancient Brains and Future AIs Have in Common?" with Read Montague
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Read MontagueGUEST
The idea is that they are broadcast systems, that at the cell body, they're given information.

Read MontagueGUEST
Those impulses run out to, let's say, a million connections, and those connections decide whether or not to cause a little bit of neurotransmitter release, dopamine release, norepinephrine release, serotonin release.

Read MontagueGUEST
They're exactly the systems that we've all sort of heard of, and we've heard of dopamine.
What we're gathering from 5,000 brains - Read Montague
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0:52speaker_0ADVERTISER
Canva, the thing that makes anything a thing.

Read MontagueGUEST
Everyone has relationships with other people, and they're interested in these relationships for a variety of reasons.

Read MontagueGUEST
Good relationships, bad relationships, annoying relationships, agnostic relationships.

Read MontagueGUEST
And what I'm going to do is focus on the central piece of an interaction that goes on in a relationship.

Read MontagueGUEST
So I'm going to take as inspiration the fact that we're all interested in interacting with other people.
6 MINS LATER
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8:06speaker_0ADVERTISER
[laughs]
How Dopamine & Serotonin Shape Decisions, Motivation & Learning | Dr. Read Montague
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Andrew HubermanHOST
... uh, dopamine signals in their noses, because, um, these are wild and cool experiments.

Read MontagueGUEST
But let me say, one thing about how we do measure dopamine in human brains, we do it in very specialized circumstances, where you are having a deep brain-stimulating electrode put into your brain to treat a movement disorder, like Parkinson's disease or essential tremors.

Read MontagueGUEST
So when you have that, and a minority of patients choose to have a small burr hole put in their head, and under careful, uh, operating room procedures, it's put down into different structures in your brain, we won't name them, and then turned on.
7 MINS LATER