Pyrroloquinoline quinone
Chemical compoundWikipedia
47
MENTIONS
15
EPISODES
14
PODCASTS
Search complete. 47 mentions across 15 episodes found for "Pyrroloquinoline quinone".
Sep 24, 2026
Sharon Hausman-CohenGUEST
It's also associated with having depression up to twenty years after a severe surgery or infection if you don't address it because IL-six inflammation in the brain is a big driver of depression.
Sharon Hausman-CohenGUEST
So what can we do to lower IL-six that has some evidence for spikeopathies? PQQ is one option.
Sharon Hausman-CohenGUEST
Um, PQQ also helps mitochondria and cognition, um, and so it's a good, uh, it, it's a good option, and it has mood studies.
Sharon Hausman-CohenGUEST
It has, um, cardiac studies, lots of different things.
Sharon Hausman-CohenGUEST
Corey also has one copy of something called HIF1A, which is hypoxia-inducible factor.
Layla MuedinHOST
This is from Louise.
Layla MuedinHOST
Dr. Hoffman, I presently take CoQ10, but I just heard of PQQ.
Layla MuedinHOST
Okay.
Layla MuedinHOST
PQQ.
Layla MuedinHOST
Pyriloquinoline.
Layla MuedinHOST
Well, I know.
Ronald HoffmanHOST
But, you know, with all the things that are available, I think there are other more plausible solutions for mitochondrial support.
Ronald HoffmanHOST
You have some experience with it, Wayla, with some of your patients?
Steven CabralHOST
Now, what about some longevity-based ones? Well, nicotinamide riboside, nicotinamide mononucleotide, which help to form NAD.
Steven CabralHOST
We might look at certain adaptogens like astragalus, or we might be using curcumin or turmeric or other great nutrients, PQQ for the mitochondria.
Steven CabralHOST
All of those are fantastic.
Steven CabralHOST
Now, those are more longevity-based.
Steven CabralHOST
gives the mitochondria energy.
Steven CabralHOST
Then I use a product called Cell Boost.
Steven CabralHOST
It has PQQ, it has astragalus, has so many great products in there that help build up mitochondria, right? So it's like, and it has nicotinamide and riboside in there too, and transfer of serotrol.
Steven CabralHOST
So like that then helps build those mitochondria.
Kent HoltorfGUEST
SS-thirty-one, think of this as an intramitochondrial antioxidant.
Kent HoltorfGUEST
So a lot of neurodegenerative diseases, just helping mitochondrial function, kind of like a super MitoQ or PQQ.
Kent HoltorfGUEST
BPC-one fifty-seven and TB four can be fragged also work.
Kent HoltorfGUEST
Melantropic peptides, alpha melanocyte-stimulating hormone.
Jared AmentGUEST
So replace the parts in the engine.
Jared AmentGUEST
We talk about something called PQQ.
Jared AmentGUEST
It's a supplement you buy on Amazon.
Jared AmentGUEST
Let's get the new mitochondria healthy and ready to go.
Will ColeGUEST
Mm.
Josh AxeHOST
PQQ, NAD+, right? A lot of these sort of, you know, in, in...
Josh AxeHOST
So I started eating more pomegranate.
Josh AxeHOST
I started doing CoQ10, doing a lot of these supplements, and I just noticed, wow, what a difference it made in my energy.
Steven CabralHOST
Now, what about some longevity-based ones? Well, nicotinamide riboside, nicotinamide mononucleotide, which help to form NAD.
Steven CabralHOST
We might look at certain adaptogens like astragalus, or we might be using curcumin or turmeric or other great nutrients, PQQ for the mitochondria.
Steven CabralHOST
All of those are fantastic.
Steven CabralHOST
Now, those are more longevity-based.
Steven CabralHOST
Gives the mitochondria energy.
Steven CabralHOST
Then I use a product called Cell Boost.
Steven CabralHOST
It has PQQ.
Steven CabralHOST
It has astragalus.
RoniGUEST
It's called Egg Quality Plus.
RoniGUEST
And so going back to our stories when we after we had our losses, I learned that women who take nutrients like CoQ10, NAC, alpha lipoic acid, PQQ, and L-carnitine, can improve their egg quality.
RoniGUEST
So we bought all those things separately.
RoniGUEST
And I thought to myself, like, just most women are a not going to do that.
Aimee RauppGUEST
You know, you and I get to see that data because we, you know, have our team that we work with and it's cool.
Aimee RauppGUEST
It's definitely like things like that are out there and they're working, but I'd PQQ, but I don't think you need every single one of them.
Aimee RauppGUEST
And I don't think, you know, taking 30 things a day, I think it confuses your body.
Marc SklarHOST
Yeah.
Scott SherrHOST
Number two is titrated hormetic completion, meaning use properly dosed acute stressors, zone two exercise, contrast temperature exposure, or hyperbaric oxygen therapy, which I know and love, as a controlled threat resolve signal that teaches the system it's safe to complete the cycle followed by real recovery windows.
Scott SherrHOST
Number three is mitochondrial nutrient support, things like CoQ10, PQQ, magnesium, and NAD+ precursors to support the metabolic machinery as a cell transitions from CDR1 through CDR3.
Scott SherrHOST
Number four, parasympathetic safety signaling.
Scott SherrHOST
So nightly vagal tone work.
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