Predimed
EventWikipedia
37
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20
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14
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Search complete. 37 mentions across 20 episodes found for "Predimed".
Oct 24, 2026
Lluís SerraGUEST
Luego, luego vieron y entonces al día siguiente sí que lo sacaron en portada, ¿no? Pero el mismo día que tocaba no lo hicieron.
Marcos VázquezHOST
Hablemos del siguiente estudio, el PREDIMED Plus.
Marcos VázquezHOST
¿Qué añade respecto a este estudio original? ¿Qué hipótesis intentaba validar o falsificar ahí?
Lluís SerraGUEST
Bueno, el estudio PREDIMED Plus no, no puedo hablar de resultados porque a pesar de que ya los conocemos, están embargados hasta que no se publiquen.
Lluís SerraGUEST
Pero básicamente lo que hacía el PREDIMED Plus, una muestra parecida, un poco mayor, randomizando dos grupos, un grupo con dieta mediterránea y otro di-- grupo con que añadíamos ejercicio físico con la intención de reducir peso.
Lluís SerraGUEST
Es decir, el PREDIMED era lo que llamamos ad libitum.
Lluís SerraGUEST
La gente comía lo que quería.
Lluís SerraGUEST
Nosotros no, no poníamos límites calóricos, pero en el PREDIMED Plus el objetivo era perder un porcentaje de-
Gil CarvalhoHOST
Yeah.
Caldwell EsselstynGUEST
Yeah, the PREDIMED study.
Caldwell EsselstynGUEST
And I can remember there was a reporter from the New York Times after the paper came out that called me and said, Dr. Esselstyn, this seems to disagree with your philosophy.
Caldwell EsselstynGUEST
What do you think of it? And the paper, and I said, well, I said, I hadn't seen it.
Kim WilliamsGUEST
They were actually saying that I had to put fish in the 2019 guideline section on nutrition.
Kim WilliamsGUEST
Because of this trial, it's called the PREDIMED trial.
Kim WilliamsGUEST
Wonderful investigators, wonderful idea.
Kim WilliamsGUEST
Take people and put them on a Mediterranean diet or randomize them to continue eating what they had been eating.
Nicola GuessGUEST
And this is really important because some critics of this study have rightly said, "Well, we're not looking at hard outcomes here.
Nicola GuessGUEST
It's just liver fat." And when we think about the cardiovascular disease, like prevention trials with diet, if we consider Predimed, what they found is the significant effect on cardiovascular events, you know, proper outcome trial.
Nicola GuessGUEST
And it, it happened through blood pressure.
Nicola GuessGUEST
It happened through improving the function of our blood vessels.
Nina TeicholzGUEST
The Mediterranean diet that performed so well in clinical trials and that has actually been studied is a diet with more than 40% fat.
Nina TeicholzGUEST
So, the famous PREDIMED study that's cited all over the world.
Nina TeicholzGUEST
So, the USDA Mediterranean diet is not the real one that's actually been tested in clinical trials.
Nina TeicholzGUEST
So this is kind of the old food politics.
AlexHOST
being healthy, if that makes sense.
AlexHOST
The next thing to look at is my favourite research study, the Spanish study called Predimed.
AlexHOST
I think I've mentioned it about a thousand times over the last few months.
AlexHOST
So this is where people were put into groups by chance, completely randomly, and then given their food directly, rather than researchers simply watching what they chose to eat.
Karen NewbyGUEST
You know, there is the data behind it, which is what's so exciting to me, which again should be making front page news that, you know, there's loads of really long studies.
Karen NewbyGUEST
There's a PREDIMED study in Spain that followed that.
Karen NewbyGUEST
older adults who were at risk of cardiovascular disease and they showed that mediterranean diet enriched with nuts helped improve their cognition scores within four years so um and then there's other studies the um the harvard nurses study which followed 50 000 women so there's a lot of women yeah but it's over two decades but it's an observational trial it's not a randomized controlled trial But an observational trial that showed that eating five portions of nuts a week improved their cognition scores in later life.
Karen NewbyGUEST
So this is a really long study.
Gil CarvalhoHOST
All right, let's look at the last three trials, and these are a lot more recent.
Gil CarvalhoHOST
So number four on our list is PREDIMED, which was published in 2013.
Gil CarvalhoHOST
103 participants with risk factors for heart disease, like diabetes, and here the majority were actually women, were put on a Mediterranean diet.
Gil CarvalhoHOST
Half of them were on a Mediterranean diet with extra olive oil.
Gil CarvalhoHOST
No significant difference between them, so about a similar reduction in both.
Gil CarvalhoHOST
And then when looking at the most compliant participants, 58% reduction in events, average of both Mediterranean diets.
Gil CarvalhoHOST
One thing to bear in mind is these individuals that had their plaque measured were a very small subset of PREDIMED.
Gil CarvalhoHOST
PREDIMED had over 7,000 participants, and the events results account for all of that.
Hana KahleovaGUEST
Even though, uh, people were allowed to eat ad libitum, as much as they wanted, they ended up eating a little bit more calories on the Mediterranean diet.
Hana KahleovaGUEST
Uh, we were, like in the PREDIMED study, we provided olive oil and we instructed the participants to eat four tablespoons of olive oil a day on the Mediterranean diet, just according to the, uh, PREDIMED study.
Hana KahleovaGUEST
And we need to realize that this by itself, uh, contains 500 calories.
Hana KahleovaGUEST
You know? Uh, it's energy-dense food.
Eric BergHOST
Now let's get to one of the biggest studies that was ever done on the diet.
Eric BergHOST
It's called the Mediterranean diet, PREDIMED.
Eric BergHOST
This is the study that a lot of doctors and the news will tell you that you will reduce your cardiovascular events by 30%, so you want to get on this diet because they proved it.
Eric BergHOST
They will usually tell you that this diet proves the prevention of heart disease, and we're talking about over 7,000 people in Spain.
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