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Post-SSRI sexual dysfunction

Post-SSRI sexual dysfunction

SyndromeWikipedia

Search complete. 42 mentions across 6 episodes found for "Post-SSRI sexual dysfunction".

Oct 13, 2026

Wild SeX

Wild SeX

Crave Theory

Oct 13 · 4 Mentions

Top 50%
Laura DelanoGUEST
92:30
So they don't even necessarily have sexual problems on meds.
Laura DelanoGUEST
92:34
When they stop, it g- goes away, and it's called PSSD, post SSRI sexual dysfunction, and it's devastating, and there are a lot of...
Laura DelanoGUEST
92:44
Like, actually, can I, can I call out a clip to look up?
Theo VonHOST
92:48
For sure.
Laura DelanoGUEST
92:49
Google PSSD Lauren Freedman.
Theo VonHOST
92:52
Uh, PSSD is a condition where sexual side effects such as genital numbness, low sex drive, and weak orgasms persist for months, years, or even decades after completely stopping selective serotonin reuptake inhibitors or related antidepressant medications.
Theo VonHOST
93:08
I will say this, I did notice that, um, my orgasms was different.
Laura DelanoGUEST
93:13
Mm-hmm.
Jay BhattacharyaGUEST
12:02
Uh, we have to answer questions that people have Right? So, uh, over-prescribing of, of, of antidepressant medication, um, uh, de-prescribing, those are really important questions, and the evidence base is, I think, only just starting to develop, and this is something I'm really, really interested in investing in as director of the NIH.
Elliot BewickHOST
12:19
Well, I wanna push you really hard on this because I've done a lot of work around PSSD, post SSRI sexual dysfunction, and I've investigated antidepressants, the way that they're described to work versus how they actually work, which no one really knows about, and whether they do work at all.
Elliot BewickHOST
12:34
I mean, uh, I don't know if you were at this.
Elliot BewickHOST
12:35
I was at the executive order with President Trump signing on Ibogaine for treatment-
Elliot BewickHOST
12:57
Yeah, it was twenty and, and I, I think that gets mixed up a lot as well oftentimes.
Jay BhattacharyaGUEST
13:01
Yeah.
Elliot BewickHOST
13:01
But people who have actually been damaged by antidepressants that have something like PSSD, at the moment, there's no light at the end of the tunnel for them.
Elliot BewickHOST
13:10
There's not really any funding going on into testing.
Teralyn SellHOST
45:55
All of them.
Jenn SchmitzHOST
45:56
I mean, my goodness, like I like, we're gonna talk about PSSD and how I'd never even like had to even understa- have a real sexual experience in my life because, again-
Teralyn SellHOST
46:05
Right
Jenn SchmitzHOST
46:05
... 16 on these meds, guys, right? Like, it changes-
Rob DewGUEST
119:58
You've heard of PTSD, right? Yes.
Rob DewGUEST
120:00
Okay, now there's PSSD.
Rob DewGUEST
120:02
PSSD.
Rob DewGUEST
120:04
It's, I guess, affecting millennials and Gen Zers more because they're over-medicated.
Adam CurryHOST
120:09
Yes, I think we've heard about this.
Lauren FriedmanSOUNDBITE_SPEAKER
120:24
My name's Lauren Friedman.
Lauren FriedmanSOUNDBITE_SPEAKER
120:26
I've become an unintentional advocate for psychiatric medication harm.
Lauren FriedmanSOUNDBITE_SPEAKER
120:30
I have a condition called PSSD, which stands for post-SSRI sexual dysfunction, which I'm sure anyone who's familiar with SSRIs knows that they cause sexual dysfunction and it's It's honestly more likely that you'll get sexual dysfunction than actually feel your anxiety or depression lessen.
Lauren FriedmanGUEST
3:26
I've become an unintentional advocate for psychiatric medication harm.
Lauren FriedmanGUEST
3:31
I have a condition called PSSD, which stands for post-SSRI sexual dysfunction, which I'm sure anyone who's familiar with SSRIs knows that they cause sexual dysfunction, and it's pretty common.
Lauren FriedmanGUEST
3:40
It's honestly more likely that you'll get sexual dysfunction than actually feel your anxiety or depression lessen.
Lauren FriedmanGUEST
3:46
But what patients are not told is that for some people, these side effects aren't side effects, but they're just permanent damage.
Lauren FriedmanGUEST
4:39
So upon getting this condition, I got it at 21.
Lauren FriedmanGUEST
4:44
I'm 23 now.
Lauren FriedmanGUEST
4:45
And I was just immediately very, very horrified that this was allowed to happen to me without my consent because PSSD is not even in the drug labels.
Lauren FriedmanGUEST
4:52
There's no...
David WayneHOST
24:39
There's an enormous amount of overlap with those people and the people who experience the horrific sexual side effects.
David WayneHOST
24:47
side effects like PSSD, post-SSRI sexual dysfunction.
David WayneHOST
24:51
That is the numbness and inability to feel sex that some people can experience even after stopping these medications.
David WayneHOST
25:01
It doesn't come with just those physical numbing side effects.

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