polymyalgia rheumatica
DiseaseWikipedia
63
MENTIONS
13
EPISODES
12
PODCASTS
Search complete. 63 mentions across 13 episodes found for "polymyalgia rheumatica".
Oct 31, 2026
Richard HorowitzGUEST
So you've got to look at that full multisystemic picture when you're trying to differentiate, for example, a rash that's a ringworm or a cellulitis versus something that's a Lyme rash where you now have these multisystemic manifestations.
Kerry GelbHOST
How about like PMR, polymyalgia rheumatica? Sometimes that pain will migrate.
Richard HorowitzGUEST
So I've only seen a couple of cases in my lifetime.
Richard HorowitzGUEST
I've been doing medicine for 42 years with 13,000 people.
Richard HorowitzGUEST
Usually with PMR, the SED rate is going to be 80, 90, 100, right? I mean, you get this massive inflammatory response.
Richard HorowitzGUEST
I've only seen a handful of cases of it.
Richard HorowitzGUEST
And in a lot of cases, there might have been some overlapping autoimmune manifestations.
Richard HorowitzGUEST
I'd have to do a search for you on that one.
Jack CushHOST
a special edition since it's the day before Halloween, and I'm Jack Cush wearing a goofy Halloween cap.
Jack CushHOST
This week on the podcast, new guidelines for PMR, certainty about good and bad beverages in gout, mixed results, and Sjogren's.
Jack CushHOST
Non-lupus drugs save lupus lives and big hips sink ships in psoriatic arthritis.
Jack CushHOST
If you can decipher that, you'll know everything about rheumatology.
Jack CushHOST
At the top.
Jack CushHOST
Novartis announced this past week that the European Commission has approved Cosentix secukinumab for use in adults with polymyalgia rheumatica.
Jack CushHOST
That would be adults with PMR not responding to or intolerant of glucocorticoids.
Jack CushHOST
This makes secukinumab the first IL-17A inhibitor approved in Europe for PMR.
Greg PainGUEST
hardware.
Tim BeveridgeHOST
I've had two full knee replacements at 45 and 54 Hashimoto's since age 14 and diagnosed PMR.
Tim BeveridgeHOST
Crikey.
Tim BeveridgeHOST
What strength exercises would you recommend once past three months post-surgery? The bone health's overall, but definitely density and more autoimmune issues developing caused by thyroid hormones.
Greg PainGUEST
hardware.
Tim BeveridgeHOST
I've had two full knee replacements at 45 and 54 Hashimoto's since age 14 and diagnosed PMR.
Tim BeveridgeHOST
Crikey.
Tim BeveridgeHOST
What strength exercises would you recommend once past three months post-surgery? The bone health's overall, but definitely density and more autoimmune issues developing caused by thyroid hormones.
Andy McDonoughGUEST
You can get really instant feedback on your cases.
Andy McDonoughGUEST
So you think someone's got PMR.
Andy McDonoughGUEST
You think somebody's got an infection.
Andy McDonoughGUEST
You get your blood back in an hour, not in a week.
Clint PattisonHOST
Does this also work for
Jose PandoGUEST
PMR? Technically, it could be, but I don't think that there's other medications that you can use that are more easily accessible and less expensive.
Clint PattisonHOST
So would you, at the moment, just for now, would you consider this particularly implantable device something that is a last resort or something as a workaround when conventional treatment fails, rather than something that is going to be a first-line approach for anyone?
Jose PandoGUEST
Like, if you look at traditionally how things have worked, and we have been doing this for a long time, is that you use with your sicker patients, and when you feel more comfortable and see the response, and you say, oh my goodness, this can work better for this or that type of patients, you begin to use it more broadly.
Martin SmithGUEST
I was seriously ill.
Martin SmithGUEST
I had PMR and giant cell arteritis.
Martin SmithGUEST
My wife had had breast cancer.
Martin SmithGUEST
She had two hip operations that have gone completely wrong.
speaker_0HOST
How do you confirm the diagnosis of polyarteritis nodosa? Biopsy or angiogram.
speaker_0HOST
Polymyalgia rheumatica is strongly associated with which other type of vasculitis? Temporal arteritis or giant cell arteritis.
speaker_0HOST
Define CREST syndrome.
speaker_0HOST
Calcinosis, Raynaud's, esophageal dysmotility, sclerodactyly, and telangiectasia.
8 MINS LATER
speaker_0HOST
She also complains of fatigue and fever.
speaker_0HOST
Labs show a markedly elevated erythrocyte sedimentation rate.
speaker_0HOST
What is the most likely diagnosis? Polymyalgia rheumatica.
speaker_0HOST
What is the treatment for scleroderma? There is no specific treatment, but you can treat the individual symptoms.
Jack CushHOST
We have a bunch of reports on vasculitis and a report- a few reports on avacopan.
Jack CushHOST
Let's start with discussion of PMR, a Danish national study of fifty-one thousand PMR patients.
Jack CushHOST
Um, half managed by primary care, half managed by secondary care MDs, I would assume that's rheumatologists.
Jack CushHOST
The incidence of PMR is a hundred and twelve cases per hundred thousand.
Jack CushHOST
That seems to be on par.
Jack CushHOST
Um, but the incidence over time, they did this between, um, over the years, uh, ten-year ic- interval, um, between them.
Jack CushHOST
But the incidence of PMR in primary care went down, but increased in secondary care.
Jack CushHOST
Hmm.
Amanda MixonHOST
[intro music] Welcome to RapCast, the official podcast of Rheumatology Advanced Practice Providers, where we bring together expert perspectives, practical insights, and meaningful conversations shaping rheumatology care today.
Amanda MixonHOST
I'm Amanda Mixon, and I am very excited to welcome you to today's episode, "The Steroid Tightrope: Managing Glucocorticoid Toxicity in PMR." This podcast is a clinical review of current approaches to the treatment of polymyalgia rheumatica, inclusive of treat to target strategy, the value of leveraging treatment based on glucocorticoid use according to the guidelines, and elements that should be taken into consideration in patients that do not achieve treatment goals, such as control of signs and symptoms and remission.
Amanda MixonHOST
Glucocorticoids remain the cornerstone of treatment for polymyalgia rheumatica, often delivering a rapid and dramatic symptom relief for patients.
Amanda MixonHOST
Because of the trade-off between the benefits and challenges of steroid use, it's critical to balance the gain against the potential harms.
Amanda MixonHOST
About half of the patients diagnosed with PMR and treated with glucocorticoids do achieve clinical response within the time and dose framework defined in the current guidelines.
Amanda MixonHOST
However, as every rheumatology provider knows, that relief can come with a cost.
Amanda MixonHOST
Many patients struggle with prolonged steroid exposure, taper-related relapses, and the cumulative burden of glucocorticoid toxicity.
Amanda MixonHOST
This can be anything from metabolic and cardiovascular complications to osteoporosis, infection risk, and just overall impacts on the quality of life.
3 more episodes mention polymyalgia rheumatica.
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