
Phosphatidylserine
4
MENTIONS
4
EPISODES
3
PODCASTS
Search complete. 4 mentions across 4 episodes found for "Phosphatidylserine".
Sep 13, 2026
How To Improve Mental Performance Dr. Peter Attia ~ Chris Williamson
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3:57Peter AttiaGUEST
Uh, phosphatidylserine and trazodone.
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3:59Chris WilliamsonHOST
And what do they do?
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4:00Peter AttiaGUEST
Phosphatidylserine, uh, in- inhibits a, a cortisol output from the adrenal glands, and trazodone is a funny drug.
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4:07Peter AttiaGUEST
It's, um, it's actually, it used to be used as an antidepressant in the '80s, but it never really took off because it had this, um, nasty side effect of making you tired.
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4:16Peter AttiaGUEST
So as SSRIs and the like came on board, it sort of fell by the wayside.
The Ritalin Generation?
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10:27Terry NaturallyHOST
And then step two, there are two additional key nutrients to help children focus.
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10:37Terry NaturallyHOST
Phosphatidylserine.
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10:41Terry NaturallyHOST
It's a phospholipid.
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10:43Terry NaturallyHOST
Natural.
Ep.574 ~ How To Improve Mental Performance - Dr Peter Attia ~ Chris Williamson
P
3:57Peter AttiaGUEST
Uh, phosphatidylserine and trazodone.
C
3:59Chris WilliamsonHOST
And what do they do?
P
4:00Peter AttiaGUEST
Phosphatidylserine, uh, in- inhibits a, a cortisol output from the adrenal glands, and trazodone is a funny drug.
P
4:07Peter AttiaGUEST
It's, um, it's actually, it used to be used as an antidepressant in the '80s, but it never really took off because it had this, um, nasty side effect of making you tired.
P
4:16Peter AttiaGUEST
So as SSRIs and the like came on board, it sort of fell by the wayside.
P
Unknown podcast
Eat These 3 Things to Sleep Better Tonight _ Psychology of Food
Aug 18 · 1 Mention
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19:51speaker_3NARRATOR
Some foods work directly against the cortisol that delays sleep.
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19:56speaker_3NARRATOR
Phosphatidylserine, a compound found in fatty fish and organ meats, has been shown in controlled trials to reduce the cortisol response to physiological stress, including the evening cortisol rise that keeps some people alert when they want to wind down.
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20:17speaker_3NARRATOR
Ashwagandha root contains withanolides that lower serum cortisol by roughly a quarter in high-stress populations over several weeks, with documented improvements in sleep onset and sleep quality.
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20:32speaker_3NARRATOR
While ashwagandha is most often taken as a supplement, it is a food by origin, and the evening cortisol pathway is increasingly understood as one of the most responsive to nutritional support.