Pharmacology
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10
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9
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Search complete. 10 mentions across 9 episodes found for "Pharmacology".
Sep 28, 2026
Joe StrainGUEST
Nereus is the brand name.
Joe StrainGUEST
Pharmacologically, it's a substance P neurokinin 1 receptor antagonist.
Joe StrainGUEST
And so basically by blocking substance P, that's involved in triggering the vomiting reflex in response to various things like motion sickness.
Joe StrainGUEST
And then chemotherapy.
Joe StrainGUEST
Nereus is the brand name.
Joe StrainGUEST
Pharmacologically, it's a substance P neurokinin 1 receptor antagonist.
Joe StrainGUEST
And so basically by blocking substance P, that's involved in triggering the vomiting reflex in response to various things like motion sickness.
Joe StrainGUEST
And then chemotherapy and and if you this like it sounds like we might have something else in the market like this and that's true we do we have a prepotent on the market already and that is indicated for like prevention of post-op nausea and vomiting or chemo prevention of chemotherapy nausea and vomiting so we we do have a drug out there that already that does work similar on this pathway but this one was specifically studied to be used to prevent motion sickness in adult patients
Jay ChaplinHOST
Berberine is marketed as a gentle, natural, safe metabolic supplement.
Jay ChaplinHOST
Pharmacologically, for your body, it's a genuinely active drug, and it messes with the machinery that your body uses to process other drugs.
Jay ChaplinHOST
In a controlled human study, berberine measurably jammed up several of the key liver enzymes, the CYP450 family.
Jay ChaplinHOST
Those metabolize a huge share of cancer drugs.
Alana CavanaughGUEST
Yeah, and biologics have been a game changer for asthma.
Alana CavanaughGUEST
Pharmacologically, one of the biggest changes in asthma management recently is that we no longer want patients relying on their short-acting beta agonists, their albuterol alone.
Alana CavanaughGUEST
And Gina actually recommends using an ICS-containing treatment plan for patients with asthma, even when they're having infrequent episodes.
Alana CavanaughGUEST
And so for adults and adolescents, Gina prefers TRACK-1, which uses an ICS-fimoterol-containing reliever, whether it's short-acting or long-acting, and then using for your maintenance and reliever therapy to be using something like MART therapy or SMART therapy, which is a single maintenance and reliever therapy all in one inhaler.
Michael SartainHOST
None of you are above that.
Michael SartainHOST
Pharmacologically, you can be induced into having a hallucination.
Michael SartainHOST
The point that I'm trying to make here is even if she induced a hallucination, she should still go to jail.
Michael SartainHOST
That's how society functions.
Michael SartainHOST
Does that make sense? By the way, estrogen is part of, wait for it, Postpartum depression.
Michael SartainHOST
That's part of it.
Michael SartainHOST
Pharmacologically, endocrinologically, you say the word, I can't say it.
Michael SartainHOST
But that's my whole point.
Jay ChaplinHOST
If you're on active cancer treatment, berberine isn't just some gentle little herb.
Jay ChaplinHOST
Pharmacologically, your body treats it like a drug, one that can significantly interact with many other drugs your oncologist works hard to pick for you.
Jay ChaplinHOST
So today, let's separate the signal from the supplement marketing.
Jay ChaplinHOST
What berberine genuinely does, what it almost certainly doesn't, and where it can actively hurt you.
Sachi LordHOST
Today we're going to talk about vasopressor pharmacology.
Sachi LordHOST
And these medications do different jobs.
Sachi LordHOST
Some raise vascular tone, some increase contractility, and some do both.
Cheryl Paxton HughesHOST
So and, and actually the medications that we're gonna be talking about with a lot of this is also coming from the same book.
Cheryl Paxton HughesHOST
We usually use Adam's Pharmacology, but it doesn't have as much information in it as the book does.
Cheryl Paxton HughesHOST
Okay.
Cheryl Paxton HughesHOST
So we just talked about the stages of labor and essentially the different things we have to do to prepare for a successful labor.
Cesar CunhaGUEST
A lot of the drugs we have now for Alzheimer's, first we had aducanumab, then we had lecanemab, and now donanemab.
Cesar CunhaGUEST
Pharmacologically, they do work quite well.
Cesar CunhaGUEST
So they do what they are supposed to do.
Cesar CunhaGUEST
They remove beta amyloid.