Peripheral artery disease

First, PAD is very, very common.

It is underdiagnosed, particularly in people with atypical symptoms.

People assume that their pain or fatigue in the leg is just aging, so don't ignore symptoms.

Second, a PAD diagnosis is an opportunity to risk stratify yourself.

It is a chance to be proactive and protect your entire cardiovascular system before a heart attack, before a stroke happens.

Welcome back to Cardiovascular Therapeutics Unplugged with Dr. Mara.

And every September, the cardiovascular world turns its attention to a condition that doesn't get nearly the airtime that it deserves,

peripheral artery disease, or also known as PAD.

Perfect, perfect.

Anything else that we can think of that's like PAD, DBT?

And pregnancy can cause swelling in the legs also, I

think.

ARPI therapy doubles the risk of grade three or higher cardiovascular events.

So how do we assess cardiovascular disease and manage it when we are starting someone and continuing someone on ADT? We want to make sure that we're doing a pretreatment assessment, assessing for any preexisting or emerging cardiovascular disease, looking at CID, PVD, CHF, arrhythmias.

There is something called an atherosclerotic cardiovascular disease risk calculation, which you can find online.

And it is a 10-year estimate that we use to guide decision-making in terms of preventative interventions like lipid management and blood pressure management.

Welcome to the heart of innovation, 60 minutes that could save life and limb with new breakthrough ideas and innovation changing the healthcare landscape.

Brought to you by Patient Advocacy Group, the global PAD association at padhelp.org in partnership with Reflow Medical, the pulse of medical ingenuity.

Here are your hosts for The Heart of Innovation, Emmy award-winning journalist and founder of the Global PAD Association, Kim McNicholas, and interventional cardiologist and founder of Save My Piggies Health and Wellness, Dr. John Phillips.

Arthritis sucks.

And there isn't too much you can do in a minimally invasive way, right? Or at least so we thought.

So looking forward to having this conversation.

It should be a fun, spirited time.

But being someone who treats PAD and telling your patients, grow those collateral vessels, grow those collateral vessels, then you're thinking, oh, God, we're going to embolize the vessels.

Large-scale

genome-wide association studies have identified common genetic variants that predict the risk of peripheral artery disease, or PAD.

In a clinical research article entitled Apologetic Risk Score for Peripheral Artery Disease and Major Adverse Limb Events, Sama El-Saeed and colleagues from Brigham and Women's and Harvard Medical School in Boston, Massachusetts, USA, assess whether a polygenic risk score, or PRS, is associated with PAD and the incidence of major adverse limb events, or MALE, independent of clinical risk factors in patients with established cardiometabolic disease.

A genetic analysis was performed, pulling individual patient-level data from six TIMI, thrombosis in myocardial infarction, trials.

The association of a recently validated PAD PRS with prevalent PAD and incident major adverse limb events acute limb ischemia, chronic limb threatening ischemia, major amputation or peripheral revascularization was assessed.

Welcome to the heart of innovation, 60 minutes that could save life and limb with new breakthrough ideas and innovation changing the healthcare landscape.

Brought to you by Patient Advocacy Group, the global PAD association at padhelp.org in partnership with Reef Slow Medical, the pulse of medical ingenuity.

Here are your hosts for the Heart of Innovation, Emmy award-winning journalist and founder of the Global PAD Association, Kim McNicholas, and interventional cardiologist and founder of Save My Piggies Health and Wellness, Dr. John Phillips.

They were talking music and wound care and you're probably thinking, what the heck, but we have an incredible team of vascular surgeons here.

We have someone from UNC North Carolina, University of Alabama.

Their bodies don't work the way they used to.

But they're struggling to live and work and do everything.

But when they have PAD...