Osteocalcin

Yeah.

Osteocalcin is released by the bone.

It goes to your brain.

It causes your brain to secrete bone-derived neurotrophic factor, which builds better neurons.

So it contradicts this statement, right? But then again, I hypothesize, I think it's because it's like T3, a lot less is doing a lot more, and it's actually broken down quite quickly as well.

But one of the things about osteocalcin, I mean, there's so many gazillion things.

Osteocalcin is the 10th most abundant protein in your body.

That's significant.

Really significant.

That's just osteocalcin.

Very interesting.

Osteocalcin also regulates the gene expression of the rate-limiting enzyme for serotonin synthesis, both in the pancreas and in the brain.

Where do our cells come from? Our bones.

But not only that, bones are master communicators, meaning they release substances, osteocalcin, that goes to the brain, stimulates production of bo- of brain-derived neurotrophic factor and builds a better brain, right? Amazing.

Osteocalcin goes to the pancreas and is involved in insulin resistance, to the gut and involved in absorption.

Um, a- another substance that the bone produces goes to the brain and is involved in satiety or how hungry you are.

Bone is this master communicator, not just dead piece of structure holding you up.