OR6A2
3
MENTIONS
3
EPISODES
3
PODCASTS
Search complete. 3 mentions across 3 episodes found for "OR6A2".
Sep 14, 2026
Kira lives for tomatoes: gardening for beginners and the science behind flavor.
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17:55AnnaHOST
It makes people hypersensitive to the soapy-smelling aldehyde chemicals, so this group of chemical compounds exists naturally in fresh cilantro leaves and in some commercial soaps.
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18:07AnnaHOST
People with this variant, OR6A2, they can pick up aromatic compounds as harsh, soapy, or metallic instead of fresh and- Citrusy, herby.
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18:20AnnaHOST
This has been reported in roughly 4 to 21% of global populations, depending on what study you're reading.
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18:26AnnaHOST
This aversion, it can vary across different ancestral and cultural groups, but you know, this is my sister, we're, we're quite closely related, and I taste just the lovely citrusy, herby wonderfulness in cilantro.
La Catrina Cantina a Mexican Cabaret in Puerto Vallarta, Mexico
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24:46Barry KesslerHOST
That's right.
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24:48Barry KesslerHOST
Uh, the soap gene causes a variation in the OR6A2 gene on chromosome 11.
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24:55Barry KesslerHOST
Of course it does.
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24:57Barry KesslerHOST
And, uh, this affects certain people who happen to be very sensitive to seriocets, which are aromatic chemicals called aldehydes.
Episode 286: Dolly’s Imagination Library, Greedy Doritos, & Pumpkin Spice Returns
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58:34Kathleen MadiganHOST
Wow.
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58:35AmyGUEST
And your, your scientific, uh, niece told me that it's a gene variation called OR6A2.
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58:42Kathleen MadiganHOST
Wow.
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58:42AmyGUEST
And it's because there's a natural compound called aldehyde, which is in the cilantro, and chemical companies make soaps, lotions, and detergents out of aldehydes.