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Search complete. 3 mentions across 3 episodes found for "OR6A2".

Sep 14, 2026

AnnaHOST
17:55
It makes people hypersensitive to the soapy-smelling aldehyde chemicals, so this group of chemical compounds exists naturally in fresh cilantro leaves and in some commercial soaps.
AnnaHOST
18:07
People with this variant, OR6A2, they can pick up aromatic compounds as harsh, soapy, or metallic instead of fresh and- Citrusy, herby.
AnnaHOST
18:20
This has been reported in roughly 4 to 21% of global populations, depending on what study you're reading.
AnnaHOST
18:26
This aversion, it can vary across different ancestral and cultural groups, but you know, this is my sister, we're, we're quite closely related, and I taste just the lovely citrusy, herby wonderfulness in cilantro.
Barry KesslerHOST
24:46
That's right.
Barry KesslerHOST
24:48
Uh, the soap gene causes a variation in the OR6A2 gene on chromosome 11.
Barry KesslerHOST
24:55
Of course it does.
Barry KesslerHOST
24:57
And, uh, this affects certain people who happen to be very sensitive to seriocets, which are aromatic chemicals called aldehydes.
Kathleen MadiganHOST
58:34
Wow.
AmyGUEST
58:35
And your, your scientific, uh, niece told me that it's a gene variation called OR6A2.
Kathleen MadiganHOST
58:42
Wow.
AmyGUEST
58:42
And it's because there's a natural compound called aldehyde, which is in the cilantro, and chemical companies make soaps, lotions, and detergents out of aldehydes.

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