Ondansetron
MedicationWikipedia
117
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67
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63
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Search complete. 117 mentions across 67 episodes found for "Ondansetron".
Sep 11, 2026
TrishHOST
And funny enough, I'm feeling so nauseated today.
TrishHOST
I've taken Zofran.
TrishHOST
Obviously, I'm not pregnant.
TrishHOST
But we're going to talk about morning sickness and why you don't have to white knuckle it.
Marianne WallisGUEST
Likely this patient's having suction events.
Marianne WallisGUEST
So if you give 500 mLs of normal saline and some Zofran for their nausea, the patient actually gets significantly better.
Marianne WallisGUEST
They feel less nauseated, and most importantly, that noise from their backpack stops happening, which is awesome.
Marianne WallisGUEST
We think in terms of really small amounts of volume when we talk about our cardiac patients, so we don't give two liters of NS to these people, mostly because their right ventricles can't handle it.
Jeff DuttonHOST
Yeah.
Tim KalpakisHOST
For the next time I get a bad hangover, I get a little trick up my sleeve where I got this prescription for Zofran, which is a – I
Jeff DuttonHOST
heard you don't mess with the Zofran.
Jeff DuttonHOST
Is that right? Sounds like he does mess with the Zofran.
Jeff DuttonHOST
I
Tim KalpakisHOST
do.
Mike HanfordHOST
Hey.
Mike HanfordHOST
Hey, speaking of
Michael BrownHOST
How is it Hassan Piker can drive a $200,000 Porsche? Was it because he was a nepo baby? Yes, he was.
Michael BrownHOST
How is it that Zofran, the Mayor Mondami of New York, how can he lecture everybody and have a beautiful, came from Uganda, and have a beautiful, comfortable, materialistic existence in the United States if it's not for capitalism? You see, for all of these people, it's just one big show.
Michael BrownHOST
They go out, they trash people, they destroy lives.
Michael BrownHOST
And then they pose that they're anti-capitalist.
TracyHOST
"I'm a huge coaster fan, so I do everything I can to help.
TracyHOST
My best options are seven days prior to travel I take Meclizine 25 milligrams prescribed by my doctor, and every night while traveling I carry Phenergan and Zofran with me for when I still get sick.
TracyHOST
Also, a vomit bag just in case I can't make it to a restroom fast enough." Okay.
LeeHOST
Interesting.
KyleHOST
My weirdest dream was whenever I, because I was in a lot of pain and like had weird nausea issues and they just kept giving me medicines.
KyleHOST
And at one point I was on some sort of like medicinal cocktail of like Zofran, Benadryl, all this stuff.
KyleHOST
One of the hospitals gave me fentanyl, which was wild.
KyleHOST
A lot of fentanyl.
KatieHOST
Mm.
AllyHOST
I would take Zofran and go out to my car and tell Matt that he needs to, like, listen for the kids because I need a minute.
KatieHOST
Tell me about the car.
AllyHOST
What?
KatieHOST
Yeah
AllyHOST
...
AllyHOST
while I wait for my Zofran to kick in, that I probably didn't even need.
KatieHOST
Yeah.
Stacey RobertsGUEST
No, I'm
Diane CarboHOST
glad you discussed that because one of the things I have clients that are on them and they're taking odonestrin, Zofran, which is for nausea, often during the week after they've been on it even for months.
Diane CarboHOST
And people aren't doing their exercises.
Diane CarboHOST
As you get older, that's one of my biggest worries is I want to stay strong and you need protein.
Rhea TemmermandHOST
So we already mentioned serotonin as part of this gut pathway.
Rhea TemmermandHOST
So does dexamethasone touch that system too? It does, but not in the same way that Zofran does.
Rhea TemmermandHOST
So Zofran or adansetron, it sits on the 5-HT3 receptor and it physically blocks serotonin from binding to it.
Rhea TemmermandHOST
Dexamethasone does two different things.
Rhea TemmermandHOST
So first it's going to reduce the actual release of serotonin.
Rhea TemmermandHOST
Most people are going to give four milligrams as the sweet spot.
Rhea TemmermandHOST
It has similar efficacy to those higher doses with a lower theoretical side effect burden.
Rhea TemmermandHOST
So as a single agent, it drops the PONV risk by about 25%, which is right about the same as Zofran and other drugs like droperidol.
Barbara HamentHOST
It's a pill or it's a liquid?
Ana SafarianGUEST
It's a, I believe, no, it's a sublingual pill that goes under the tongue that kind of like, how do you say it? Just like a Zofran.
Barbara HamentHOST
Dissolves right away.
Ana SafarianGUEST
It dissolves right away.
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