Skip to main content
Nucleotide

Nucleotide

Search complete. 11 mentions across 6 episodes found for "Nucleotide".

Nov 6, 2026

Julie RyanHOST
23:10
And we're going to do a DNA healing on him.
Julie RyanHOST
23:13
Last, and DNA, of course, is the recipe that tells the cells how to behave, comprised of four nucleic acids represented by four letters, A-T-C-G.
Julie RyanHOST
23:25
One strand can have anywhere from 100,000 to a billion letters on it, and I'm watching those letters get resequenced.
Julie RyanHOST
23:33
So we're taking the DNA back to a normal recipe.
Erik WinfreeGUEST
14:05
It almost suggests that sort of all the functions for a living cell or a living entity or a living whatever it is, and evolving whatever it is, could have been supported by RNA.
Erik WinfreeGUEST
14:15
And if you look at it sort of from a mathematician's point of view, you know, what is RNA? It's a string of A-T-C, well, A-U-C-G, very similar to DNA's A-T-C-G.
Erik WinfreeGUEST
14:28
One might argue that DNA also, if it has the same kinds of capabilities, is sufficiently rich in its behavioral repertoire to support all the things that life needs without the proteins, without the RNA, and so forth.
Sean CarrollHOST
14:45
And I know that there are four nucleotides that play the role in DNA.
Ed BoydenGUEST
9:17
You have all sorts of interactions between chromosomes.
Ed BoydenGUEST
9:20
Are any of those complex phenomena reliable enough and describable enough and repeatable enough and so forth that you could call it ground truth? Maybe, but it's also possible that we're not there yet, right? We don't know what's fundamental beyond the ATCG.
Ed BoydenGUEST
9:33
It's quite possible that there are a lot of fundamental things that are there, but we just don't know them yet.
Ed BoydenGUEST
9:38
One example, I guess, would be the genetic code, right? We have a triplet code where three bases will specify an amino acid.
Valeh AmiriGUEST
41:15
Well, I think one of the problems that we mentioned earlier was that input times gradients doesn't, like, in the case of one hot encodings, doesn't really make sense.
Valeh AmiriGUEST
41:23
Uh, like, the perturbation of ATCG to, from one zero zero zero to, uh, one plus epsilon doesn't really make sense-
speaker_2HOST
41:32
Mm-hmm
Valeh AmiriGUEST
41:32
... because one plus epsilon is not a one hot encoding sequence.
Ryan PayneHOST
1:09
So yes, I will mourn.
Ryan PayneHOST
1:12
I would assume that he, 'cause he likes to throw in little references to, to other IPs in his stuff, so, uh, I would expect that Master Chief was going to mow down a bunch of ETs.
Ryan PayneHOST
1:23
That would be awesome.
Donnie G RetroHOST
1:24
Yeah, I was just thinking that.

14 MINS LATER

Blue WilliamsHOST
15:16
...
Blue WilliamsHOST
15:16
Xbox employees announcing a new initiative called Xbox Labs.
Blue WilliamsHOST
15:21
Claiming to be inspired by a bunch of vibe-coded decomp projects she saw online, the initiative itself aims to take those projects and turn those concepts into something that Xbox players can actually play.
Blue WilliamsHOST
15:32
Taken at face value, the memo sounds as though Sharma got a shotgun blast in the face of X's algorithm and decided to run with it, seeing the flood of infinite posts that get pushed into the feed on the site.
Ryan McClearyGUEST
33:21
Um, and this is all lots of, you know, lots of sequence data.
Ryan McClearyGUEST
33:25
So looking at ATCG over and over again.
Ryan McClearyGUEST
33:28
Um, and luckily there's computer people that are way smarter than I am that can take a whole bunch of data and distill it down into some, some easier answers.
Mark KyleHOST
33:37
I'm sure they're using AI these days too to help that as well.

We value your privacy

We use cookies to understand how you use our platform and to improve your experience. Click “Accept All” to consent, or “Decline non-essential” to opt out of non-essential cookies. Read our Privacy Policy.