Nonsteroidal anti-inflammatory drug

And typically the most common, you know, in today's world, not so much opiates, but these are still prescribed.

And then you get what are called non-steroidal anti-inflammatories, NSAIDs, drugs like ibuprofen.

or meloxicam, so again, these are drugs that reduce pain post-surgically, so basically they're trying to provide you comfort after the surgery is over.

But a lot of people don't realize that some of the side effects of the antibiotics is they reduce B vitamins.

So again, these medicines deplete these very key nutrients that your body's gonna need more of in order to overcome the scheduled trauma of the surgery itself.

And then you also have non-steroidal anti-inflammatories and these will reduce folate.

There's a number of studies showing that NSAIDs lower folate, which folate is necessary for the protein synthesis around your, especially if you're having like a joint surgery.

So like you need folate to make new cartilage.

Then the sore muscles aren't sore, now they're bigger and stronger.

If you take a shitload of NSAIDs and do a bunch of cold plunges, yeah, you'll feel much better very soon, but you didn't grow any muscle.

And these all things are cold and NSAIDs are confirmed to reduce the amount of muscle growth you get.

So these are masking things.

They're not helping you recover.

Cold, heat, et cetera, they don't do that.

They just don't.

You mentioned NSAIDs, maybe a little bit extreme, but what about recovery supplements?

Clinical pearl.

Decreased volume of distribution, such as in intravascular hypovolemia or the elderly population, impaired renal function, and the use of certain medications including thiazide diuretics, ACE inhibitors, and NSAIDs will all increase lithium levels.

Increased volume of distribution, in cases like increased total body water, such as during pregnancy, and increased dietary sodium, caffeine, acetazolamide, and theophylline will reduce lithium levels.

What are some long-term side effects of lithium use? In addition to monitoring for short-term side effects of both acute and chronic toxicity, it is important to consider long-term side effects of lithium use.

If you've ever heard the term COX inhibitor, That's what ibuprofen is.

It's the mechanism of action of the common class of medicines called NSAIDs, non-steroidal anti-inflammatory drugs.

And there's a number of different types.

If you've ever taken Celebrex or ibuprofen or naproxen or diclofenac, then you've taken an NSAID with the whole explicit purpose of trying to reduce your pain.

The management of the disease is a combination of pharmacological treatments as well as non-pharmacological interventions, i.e. surgery, physical therapy, chiropractic care, some people do other alternatives like acupuncture, ultrasound therapies, and a number of other laser, cold laser therapies.

That's all non-pharmacological invention, right? But pharmacological treatments include paracetamol, Tylenol, non-steroidal anti-inflammatory drugs, and chondroprotectives like glucosamine and chondroitin.

NSAIDs long-term use associated with serious adverse effects.

So if you're on NSAIDs for long periods of time, there's an adverse effect and it's gastric bleeding.

And so when we try to exercise and the muscles are too tight, the cartilage on the joints grind and it creates inflammation.

So now, after that, we end up taking a medication for pain those kinds of medications are called NSAIDs non-steroidal anti-inflammatory drugs and so NSAIDs deplete the body of iron folic acid and vitamin c and of course those things can contribute to muscle and joint pain so again we're chasing our tail The next thing that we know that magnesium deficiency can contribute to is a thickening of the blood.

So it causes an increase in blood viscosity or increases the thickness of the blood.

Now when that happens blood pressure goes up.

And they put a scan up and they're like, oh, there's the problem.

And I went through the normal kind of standard of care, which is take some NSAIDs, stay off the leg.

If you're that age, you're going to get better.

You know, you've got the hormones like a Greek god at that point.

They can also inhibit lipoxygenases.

And what we found in these cellular systems that I've just described, M1, M2 macrophages, is that some of these NSAIDs, COX inhibitors, they suppress prostaglandin formation, but at the same time also SBM formation, because they probably inhibit 15 locks pathways activation pathways and partly also in the 5 blocks.

So they are not really helpful for 5 blocks inhibitors.

We have to consider that some of the, like, some resolvents and in particular like toxins require 5.

Day four, you can start adding some activity back.

In our recovery protocol, day four is when we begin allowing NSAIDs and mild exercise with activity progressing as tolerated.

Now the key phrase here is as tolerated.

You can start exercising, but it should be a gentle warmup.