So let's just talk a bit about when we first connected and what you do.

Yes, I think we were, it was during COVID or just around the time and we did quite a bit of work with Tim Spector.

And you had a conversation with him about the differences between, pre-menopause, post-menopause with COVID.

And we thought that was super interesting.

So I asked him to connect us and to do some research together.

So I think that's where it originally started.

And I liked the whole immunology side that you brought to the conversation because that really wasn't there.

And we can't keep ignoring proper data, can we?

Obviously, the picture is quite complex, but

now, luckily, the black label has been removed, so it's not connected to breast cancer.

And there was this one big misconception that was advertised 20 years ago after the Women's Health Initiative.

where they went out publicly to claim that this causes breast cancer, which was later on found to be incorrect.

So I think that was the...

And 20 years ago, the use of HRT was up in the 30s, even 40s globally.

Now it's below 5%.

And

And it's really nice that you have this full service.

Yes, I mean, our core value is really, in the end, finding a solution for you.

And everybody's very unique and very complex.

And I think for that, the AI helps, the human also helps.

The test captures something you wouldn't get in other markers.

So that's very common.

We would see changes, even when we look at disease-specific changes, we see these changes in glycans up to 10 years, compared to symptoms and the diagnosis.

But

It would be interesting to see your thoughts.

It would have.

So it would definitely have an impact.

So it's a shame you don't have this period.

But of course, things will happen through life.

So your results will also change.

But the one you did here, so you did a test back in March, right? And I'm just going to open the one with your results.

I feel as well, like got to optimize where you're going to die.

Mm.

It's gonna happen to everybody.

And then there's a question, is it medically necessary to treat it? And I think absolutely now we agree, yes, because all of those symptoms that have an effect on general quality of life, um, and all of the long-term health consequences, they're worth the benefit.

But because there was this small risk that was publicized as breast cancer, which we now know is actually not connected to the estrogen, might have been connected to the synthetic progestogen, and it was incredibly small, um, 1.26%, which is just above being si- significant.

And as an example, if you're a smoker, you have a 27.6% increased risk of lung cancer.

Okay.

So you can personalize it to, to an individual woman, and that then hopefully will correspond to their long-term outcomes as well.

So I'd say hormones are the next one, for men as well, and, um, there we see that it's not about the level of testosterone, it's the conversion of testosterone to a healthy level of estrogen.

What are we talking about then when we're saying glycan age versus chronological age or biological age versus chronological age? Because a lot of people don't even understand that.

So there's many theories of what aging is.

So there's 12 hallmarks of aging.

Now there's going to be more as they expand their understanding of biology.

But one key driver of aging is inflammation or something called inflammation.

So this was first coined as a theory 25 years ago by an Italian scientist called Claudio Franceschi.

So he was connecting that to health decline.

How many twins were there? A thousand twins over 20