I wonder if you could talk about why the intensivist should learn more about ketamine, because I know there's a, a population out there that still has a, a very negative feeling towards that medication.

You know, it, it's funny you say that as far as, you know, the, kind of the negative feeling about it and, and your personal use of it has been beneficial.

You know, ketamine's one of those drugs where it ebbs and flows.

It's kinda like the new fashion statement.

It's in one year, and the next year it's out.

And then it's in the next year, [chuckles] and it, it just kinda is like a rollercoaster.

You know, there's a new ketamine drug on the market or something changed with the pharmacokinetics of the drug per se.

And Nathan, coming back to ketofol or ketamine and propofol, what are things that clinicians should be looking at with that combination in the ICU?