Mosaic

When anatomy is asymmetric, think spatial biology.

Mosaicism, mixed gonadal dysgenesis, ovo-testicular tissue, regional differences in gonadal determination.

Blood karyotype is not a whole-body census.

Serum hormones are not side-specific measurements.

And this is what it leaves, let's say, what is called a mosaic of bad work.

A bit of this cell is edited, this cell is not edited.

Mosaicism can cause some specific diseases after in life, but also it can be completely harmless.

Another problem it can be that it can make IVF testing of biopsies not reliable because for example doctors when they're gonna test an embryo they do a biopsy and they check very specific they check specific cells it could happen that they only check unedited cells or only check edited cells and the rest of the mutated cells are not let's say contemplated by this biopsy And this could give parents false reassurance or even doctors false reassurance on how the embryo is developing.

Both Niarchan and Egli's studies were thoroughly examined in the scientific community.