Michaelis–Menten kinetics

J.B.S. Haldane, aside from population genetics, was also the first to realize the theoretical possibility of, and experimentally demonstrate, genetic linkage in mammals.

He also proposed the now-famous primordial soup hypothesis of the origins of life, and he even authored the modern formulation of the Michaelis-Menten equations of enzyme kinetics.

Haldane was also the first to note a link between malaria and the prevalence of genetic blood disorders in tropical regions.

In 1948, he hypothesized that certain genetic diseases, when inherited in the heterozygous state, could be protective against malarial infections by deforming red blood cells and making them inhospitable for the malaria parasite.