Methicillin

But what convinced me isn't the projection of antimicrobial resistance, it's the history.

Methicillin came into wide use in 1959, and the first resistant staph showed up in 1960, just one year later.

Consider that bacteria reproduce roughly every 20 minutes, where we humans only reproduce maybe twice in a lifetime.

So this speed of replication is directly tied to how quickly antimicrobial resistance can emerge and spread.