
Mary-Frances O'Connor
Psychologist and professor
6
APPEARANCES
5
PODCASTS
012
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Sep 14, 2026
The Physiology of Grief: What Loss Actually Does In Your Body with Mary-Frances O'Connor, PhD.
22:37
One is it is important to remember that while the risk is higher on that day, the risk across the whole population is still very low for having a heart attack, right? So what I mean to say is that we know from research that the most common reaction to the death of a loved one is actually resilience.
23:03
So, you know, it's this funny thing about statistics that you can, that you can see that resilience can be the most common response and also be worried about these instances of a sudden cardiac event.
23:25
Pregnancy is not a disease, right? But no one would suggest that pregnancy isn't physiological.
9 MINS LATER
Why Your Brain Still Expects the Person You Lost with Dr. Mary-Frances O'Connor
M
4:08But there are these rare situations where that person isn't out there anymore.
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4:32It's a learning curve to understand everlasting doesn't mean the same thing now.
3: This is Your Brain on Grief: How Loss Changes Your Brain, Body & Identity with Dr. Mary-Frances O’Connor
37:11

John OnwuchekwaHOST
Did you have more guilt because you're like, oh man, I can't believe I felt a solution or a type of relief when she...
24 MINS LATER
S
61:29speaker_2UNKNOWN
pray.
The Grieving Body: How to Heal After Loss with Dr. Mary-Frances O'Connor
41:51
Now, if that was a death, eventually there is a second classic response that we see.
41:57
We see this in animals, we see it in infants, and this response we call despair.
42:03
And that is, "Oh no, they're gone." And even just hearing it, you can feel how physically different that is from protest, can't you? You can feel the withdrawal.
42:22
What's important is that the information, oh no, they're gone, is the same in both cases.
42:30
It's our response to that information that is completely different and is completely physical, right? And so what's notable here is despair is important.
6 MINS LATER
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49:12Forrest HansonHOST
How do you think about prolonged grief, maybe connecting it to what you're talking about now, which I think is a really interesting frame for it?
The Science of Love (Episode 3)
15:50
Our cardiovascular system is tethered to the external pacemakers that are our relationships.
16:04
In the first 24 hours after the death of a loved one, we're 21 times more likely to have a heart attack than any other day of our life, which is an absolutely shocking statistic.
16:18
Eventually, as we learn day after painful day, we come to recognize that we can't expect them anymore.
16:30
It is about overcoming our brain's belief that they will always be there, which takes a very long time to truly understand.
K
16:46Kate Parkinson-MorganCORRESPONDENT
One way to process the loss while honoring our loved ones is through memorials or rituals to mark birthdays or other major holidays.
Healing From Grief & Loss | Dr. Mary-Frances O'Connor
32:23
And we used to say, in the summers we saw our cousins for weddings, and in the winter, we saw our cousins for funerals.
32:30
I saw numerous deceased bodies as a child of my family members while running around playing tag with my cousins.
28 MINS LATER
