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Mark Abie Horowitz

Mark Abie Horowitz

Researcher and neuroscientistWikipedia

Search complete. 6 mentions across 5 episodes found for "Mark Abie Horowitz".

Sep 10, 2026

Josef Witt-DoerringGUEST
33:58
I know a lot of people are going to hear this and they're going to say, this doctor's talking off the top of his head.
Josef Witt-DoerringGUEST
34:03
But when we've looked at surveys, a group of researchers, Mark Horowitz, Joanna Moncrief out of the King's College London, John Reed, he's another researcher over there, they did a survey of people coming off antidepressants.
Josef Witt-DoerringGUEST
34:17
10% of people had withdrawal symptoms lasting longer than a year coming off.
Josef Witt-DoerringGUEST
34:20
Okay, that's 10%.
Josef Witt-DoerringGUEST
11:38
But that has changed because a bunch of researchers led by Dr.
Josef Witt-DoerringGUEST
11:45
Mark Horowitz, Joanna Moncrief, they started doing surveys on people coming off these drugs.
Josef Witt-DoerringGUEST
11:50
And what they found was that 33% of people could not come off these medications even though they wanted to.
Josef Witt-DoerringGUEST
11:57
And they found that 47% of people had severe withdrawal symptoms coming off.
Joseph Witt-DoerringGUEST
11:05
I, I mean, thankfully more and more.
Joseph Witt-DoerringGUEST
11:07
I mean, there's Mark Horowitz in the UK, and a lot of people are reaching out now and doing my wife's, uh, deprescribing mentorship program.
Joseph Witt-DoerringGUEST
11:14
And so there's a lot of junior doctors and NPs who have become really passionate about holistic psychiatric care.
Joseph Witt-DoerringGUEST
11:21
So we are multiplying.

29 MINS LATER

Joseph Witt-DoerringGUEST
40:36
And essentially, based on nothing, 'cause you can look at the paper, based on data that doesn't even make sense, they said antidepressant withdrawal is mild and self-limiting, which means that it goes on for, like, two weeks.
Joseph Witt-DoerringGUEST
40:48
And there, there, there just wasn't a clear clinical rationale that that was what was happening to everyone.
Joseph Witt-DoerringGUEST
40:54
Now, thankfully over the last, like, six or seven years, mostly due to Joanna Moncrieff and Mark Horowitz in the UK, it's a, a group of very dedicated researchers over there.
Joseph Witt-DoerringGUEST
41:03
They're doing a lot of surveys.
Paul MasonHOST
28:59
Fortunately, we've got people like Dr.
Paul MasonHOST
29:01
Mark Horowitz, who has helped us out with the Maudsley deprescribing protocol for But again, this is even far more complex and a bit more nuanced than proton pump inhibitor deprescribing.
Paul MasonHOST
29:15
So the thing about antidepressants is that The way a drug works is it goes onto a receptor in the brain and you might have 100 receptors and then you might have 50 of them filled up by drug and being active.
Paul MasonHOST
29:32
But with the antidepressants, the number of drug receptors or the occupancy of the drug receptors decreases.

Unknown podcast

Psychiatric Medication: Effectiveness, Side Effects & Withdrawal Risks

Aug 16 · 1 Mention

speaker_1UNKNOWN
22:23
For context, this is basically the gold standard, most authoritative medical text on the risks of psychiatric drugs in the world, authored by Professor David Taylor and Dr.
speaker_1UNKNOWN
22:32
Mark Horowitz.
Joannes WyckmansHOST
22:33
So this isn't fringe science.
Joannes WyckmansHOST
22:35
This is the top of the medical pyramid.

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