Leonard Hayflick
American anatomist and former president of the Gerontological Society of AmericaWikipedia
10
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7
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7
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Search complete. 10 mentions across 7 episodes found for "Leonard Hayflick".
Sep 18, 2026
Alex KessenHOST
But still, mailing a lethal weapon, like [chuckles] I can't even imagine how that went down.
Alex KessenHOST
And it kind of makes me wonder, when exactly did these sort of informal handshake agreements in science stop being a thing? If you recall from a couple of episodes ago in our geron story, the father of gerontology, Leonard Hayflick, drove his cell cultures cross-country from Pittsburgh to Stanford right around this time that Schantz does this.
Matthew PechHOST
Yep.
Matthew PechHOST
Absolute Wild West biology.
3 HRS 7 MINS LATER
Matthew PechHOST
The other personal bookend to a story that began in nineteen forty-eight is Gavin Herbert Jr., the founder's son, Allergan's first salesman out of the back of his car, and CEO from nineteen sixty-one to nineteen ninety-one.
Matthew PechHOST
Gavin is now in his mid-nineties, still working and still spry.
Matthew PechHOST
He chairs Rogers Gardens, a garden store his father started, among other ventures, including a groundwater remediation company.
Matthew PechHOST
When asked about the enduring magic of the franchise, Gavin gave us the ultimate retrospective on what makes the asset so singular.
Bill AndrewsGUEST
So when you actually have, when those cells divide a total of 100 times, you can't divide anymore.
Bill AndrewsGUEST
We have a limited number of times our cells can divide called the Hayflick limit and inflammation, oxidative stress accelerate that.
Bill AndrewsGUEST
So One thing I always say first is, and I don't get any compensation for saying this, but there's a test called the ALCAT test, which is something that people, if they Google it, they can find out where to get it from.
Bill AndrewsGUEST
You just have to say test because if you just say ALCAT, you'll get Alcatraz.
AlexHOST
They took human fetal fibroblasts, so cells in a petri dish, and applied the synthetic peptide.
AlexHOST
Normally, these specific cells hit a hard biological wall called the Hayflick limit.
JessicaHOST
Right.
JessicaHOST
And in those specific fetal fibroblasts, the Hayflick limit is reached at roughly 34 cellular divisions.
AlexHOST
OK.
JessicaHOST
After that 34th division, the photocopier just shuts down.
Nathalie NiddamHOST
Yeah.
Rafael GonzalezGUEST
And, and what, what transpires is, you know, first of all, every cell in the body has a finite amount of divisions, which is called the Hayflick limit.
Nathalie NiddamHOST
Yeah.
Rafael GonzalezGUEST
And even your immune system does, so your immune system's supposed to turn over.
Ken BerryHOST
There may be an even easier way to get the life extension benefits touted when it comes to caloric restriction without actually having to starve to death for the rest of your life to attain it.
Ken BerryHOST
I'm Dr. Ken Berry, a family physician, and I've been interested in life extension since Dr. Hayflick published his book.
Ken BerryHOST
Let's talk about this.
Ken BerryHOST
Using caloric restriction, scientists have been able to extend the lifespan of many different animals over the decades.
Bill AndrewsGUEST
Like, how do we age? Why we age was still a question, but how do we age? Yeah.
Bill AndrewsGUEST
And there had been a study published in 1961 by Leonard Hayflick that showed that human cells can only divide a certain number of times.
Bill AndrewsGUEST
We're limited.
Bill AndrewsGUEST
Our cell division is limited.
1 more episode mentions Leonard Hayflick.
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