KNDy neuron

So a little kind of background on this and this mechanism.

Essentially what neurokinin normally does is bind to this receptor, this neuron known as the kispeptin neurokinin dynorphin receptor or neuron, which is kind of a mouthful, but they actually abbreviate that and they call it candy, K-N-D-Y.

That's how they, how they abbreviate it.

And that moderates activity in the hypothalamus.

My body is going to tell me to wake up at 3.45. 3.50 a.m. And so that is all happening.

And there's some really cool things in the brain called candy neurons, which you're going to hear more and more about.

I'd love to come back and talk about candy neurons in the brain.

And so we've got drugs targeted towards these candy neurons now.

So estrogen is the deficiency factor.

And these candy neurons are getting hypertrophied in overdrive and they're lighting up the thermoregulatory center.

Well, on those candy neurons is something called substance P, and that is interfering with a woman's sleep.

So some of these drugs are targeted towards that substance.