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Karl Deisseroth

Karl Deisseroth

American neuroscientist and physicianWikipedia

Search complete. 215 mentions across 152 episodes found for "Karl Deisseroth".

Oct 16, 2026

Nicholas WeilerHOST
12:44
[laughs] Um, yeah, optogenetics is definitely in the news this week.
Nicholas WeilerHOST
12:49
Um, very exciting that Stanford Neuroscience has had this amazing moment in, um, in the sun with the recognition of the work of Karl Deisseroth.
Nicholas WeilerHOST
12:57
That work actually had just come out, the big, uh, 2005 paper introducing optogenetics, um, just a couple of years before I started graduate school.
Nicholas WeilerHOST
13:08
So it was very much in the air.
Krishna ChoudharyHOST
4:39
Optogenetics won the medicine prize.
Krishna ChoudharyHOST
4:42
Specifically, they recognized Karl Deisseroth, Peter Hegemann, and Gero Nagel for discoveries concerning light-gated ion channels and optogenetics.
Krishna ChoudharyHOST
4:51
Those are the three with their artwork.
Krishna ChoudharyHOST
4:53
Um, this is a technology that allows neuroscientists to turn on and off specific neurons in the brain using light, and this allows scientists to establish causal links between stimuli, neur- neural firing, like the activity of neurons in the brain, and behavior of the animal at large.
speaker_1SOUNDBITE_SPEAKER
43:22
One of the best candidates right now is carmine, a protein found in a marine microbe that responds to red light.
speaker_1SOUNDBITE_SPEAKER
43:28
It's so sensitive that in 2021, Deisseroth's group shone 635 nanometer light, red light, through an intact skull of a rodent and switched on neurons up to seven millimeters deep with millisecond precision and no surgery required at all.
speaker_1SOUNDBITE_SPEAKER
43:43
This work is still in development and may be for a very long time before we ever get to the point where we are reprogramming the reward centers of our own brain using light.
speaker_1SOUNDBITE_SPEAKER
43:53
But the impact of optogenetics has already been felt across the full study of the human brain.
Matilda SercombeHOST
3:52
[ding] Fact number five.
Matilda SercombeHOST
3:54
The 2026 Nobel Prize for Physiology or Medicine went to Karl Deisseroth from the United States, as well as two German scientists, Peter Hegemann and Georg Nagel.
Jenny LynchHOST
4:07
This prize was for something called optogenetics, which is a tool that's used to study how the brain works.
Jenny LynchHOST
4:13
The opto part means light, and the genetic part is about DNA.
Jenny LynchHOST
5:17
The technique involves using light to turn cells on or off and observing what happens.
Matilda SercombeHOST
5:23
Optogenetics has become a really important tool in neuroscience, and it is a good example of how long it can take for a new idea to work.
Jenny LynchHOST
5:32
Karl Deisseroth was working on optogenetics for at least 20 years before he won the Nobel Prize for his work, and he has said that the work of lots of scientists before him was really important and that his work was built on the work of others.
Jenny LynchHOST
5:44
This is often how scientific discoveries are made.
Gary ArndtHOST
8:41
Together, Hall and Woodford helped build a more detailed understanding of how individual economic decisions and expectations drive economy-wide fluctuations, giving policymakers better tools to study inflation, recessions, and monetary policy.
Gary ArndtHOST
8:56
The 2026 Nobel Prize in Physiology or Medicine was awarded to three men, Karl Deisseroth of Stanford, Peter Hegemann of Humboldt University of Berlin, and Georg Nagel of the University of Würzburg, Germany.
Gary ArndtHOST
9:09
The Nobel Committee recognized them, quote, for their discoveries concerning light-gated ion channels and optogenetics, end quote.
Gary ArndtHOST
9:18
So what exactly does that mean? For centuries, scientists have struggled with a fundamental problem in neuroscience.
Gary ArndtHOST
10:16
Because moving ions creates electrical charges, these proteins can act as light-controlled switches.
Gary ArndtHOST
10:24
Peter Hegemann and Georg Nagel helped discover and characterize these light-sensitive proteins, demonstrating how they could control electrical activity.
Gary ArndtHOST
10:33
Karl Deisseroth and his collaborators subsequently developed techniques for inserting genes that produce these proteins in mammal neurons.
Gary ArndtHOST
10:41
And the result was revolutionary.
KimHOST
2:16
It's been a good Nobel season for Stanford.
KimHOST
2:19
Last week, Professor Karl Deisseroth shared the medicine prize for work that uses light to stimulate nerve cells in the brain.
KimHOST
2:29
Giving police a false tip is never a good idea, but AI did it anyway.
KimHOST
2:35
Anthropic admits that over the summer, one of its earlier models sent the Philadelphia PD an untrue clue about an unsolved crime, but nobody at the company noticed the blunder until September and didn't reach out to police until last week.

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Oct 13 · 1 Mention

ElizabethHOST
5:22
Speaking of looking carefully, today's Nobel started with an alga that swims toward the light.
RoryHOST
5:32
The 2026 Nobel Prize in Physiology or Medicine has gone to Karl Deisseroth, Peter Hegemann, and Georg Nagel.
RoryHOST
5:40
The citation is their discoveries concerning light-gated ion channels and optogenetics.
RoryHOST
5:45
Announced on 5th October.
Eliana FischelGUEST
0:07
You're listening to Rooted and Rising, featuring weekly sermons from Washington Hebrew Congregation.
Eliana FischelGUEST
0:13
This week, Dr. Karl Deisseroth, I do not know if I'm saying that correctly- [laughs] ... uh, received the Nobel Prize in Science and Medicine.
Eliana FischelGUEST
0:24
I could not begin to describe to you why he received that prize.
Eliana FischelGUEST
0:28
[laughs] That's so beyond, uh, my expertise.
JTHOST
40:17
Sure.
Jonathan SavageCORRESPONDENT
40:17
First of all, for medicine, Karl Deisseroth.
Jonathan SavageCORRESPONDENT
40:20
He wa- is sharing the prize for optogenetics.
Jonathan SavageCORRESPONDENT
40:24
Um, they've been working to use light to control, uh, nerve cells in the brain, um, to investigate things like Parkinson's disease and epilepsy.

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