Journal of the American Heart Association

Now, here's a study that makes this gene genuinely useful.

In 2017, Rita Schuller, Andreas Pfeiffer, and colleagues in Germany published a study in the Journal of American Heart Association, and it used healthy twins.

First, they ate a low-fat diet for six weeks, then they switched to a high-saturated fat diet for six weeks, heavy on red meat, sausage, bacon, and four-foot-fat dairy.

On the high-saturated fat diet, everyone's ACE level went up by about 15% on average.

Most famously, there was a systematic review written by Katsanos et al.

and published in the Journal of American Heart Association in 2018.

Using data from 28 randomized controlled trials, Katsanos concluded that while Paclitaxel devices were safe at one year, they were linked to an increased risk of all-time mortality at two years, risk ratio of 1.68, and even more so at five years, risk ratio of 1.93.

Compared to uncoated devices, they also pointed out a potential dose-response relationship showing an excess of risk of death per milligram year of paclitaxel exposure.