Intrinsically photosensitive retinal ganglion cell

And Lazzarini, Osprey, Pruski, and Hattar, in the Annual Review of Neuroscience in 2017, put forward an alternative.

They argue light's effect on mood may run through an IPRGC-dependent mechanism independent of circadian disruption, meaning light might affect mood directly, not only by moving the clock.

So, two models.

Light moves the clock, mood follows.

Where they get the science wrong is about the, the impact of light on the eyes and how that relates to the brain.

There is a cell receptor inside the eye called an ipRGC, an intrinsically photosensitive retinal ganglion cell.

So that's, that's the mouth, that, that's the huge vocab word of the day.

Yeah, that's pretty impressive.

They indirectly get to your circadian clock through these intrinsically photosensitive retinal ganglion cells.

But I was just looking at the IPRGCs, which light hits them, talks to your circadian clock.

And when I would shine blue-green light, they would go crazy.

They'd be like, "Oh my God, this is...