insitro
insitro is the physical AI company unlocking causal human biology, founded and led by AI pioneer Daphne Koller. By generating the world’s largest integrated multi-modal corpus of human and cellular data, we’ve built the Virtual Human™ – a genetically anchored causal AI engine that reveals how disease begins, progresses, and can be resolved. Our platform enables us to precisely identify causal genetic drivers and deploy our TherML™ AI platform to design optimal medicines, advancing a broad pipeline of therapeutics for neuroscience and metabolic diseases. This industrialized architecture creates a self-learning loop: with every biology we onboard, our predictive models grow smarter, accelerating discovery across scales of biology. Join us in transforming the future of medicine!www.insitro.com
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Search complete. 4 mentions across 3 episodes found for "insitro".
Oct 15, 2026
SamHOST
We really need to be precise about what the machine learning is actually doing here.
SamHOST
We talk about lab-grown cell models, but what InCitro is specifically using are induced pluripotent stem cells.
SamHOST
Right.
SamHOST
We should probably take a second to explain what
SamHOST
That's a little cynical, don't you think? No, I think it's realistic.
SamHOST
My concern is the structural issue of who ultimately bears the risk here.
SamHOST
InCitro uses their AI forensics to find the targets and advance the candidates.
SamHOST
But once they reach candidate status, AstraZeneca takes over.
Ian QuigleyGUEST
Sequencing DNA is another way of taking pictures, uh, and so it's basically pictures in DNA sequencing.
Ian QuigleyGUEST
And if you can shovel your, uh, challenging problem, uh, into that using one of those approaches as a readout, uh, so for, you know, like Recursion takes actual pictures of cells, and a bunch of other groups do that, like Insitro does that.
Ian QuigleyGUEST
And then almost everyone else with the spatial omics stuff or, or other approaches, they'll do some mixture of, of pictures and, you know, and sequencing, which is, is also pictures.
Ian QuigleyGUEST
Yeah.
speaker_0HOST
But the tradeoff is time, right? Proving a brand new biological target works takes significantly longer than what Insilico is doing.
speaker_1HOST
It does, which is why InSitro has less clinical evidence right now.
speaker_1HOST
It is a much longer, riskier game.
speaker_1HOST
Yeah.