Hydrochloric acid
Chemical compoundWikipedia
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Search complete. 59 mentions across 21 episodes found for "Hydrochloric acid".
Sep 23, 2026
SadieHOST
Mm-hmm.
NatalieHOST
Now we're gonna talk about something that sounds kind of similar but is definitely not similar, and that's hypochlorous acid, or HCl.
SadieHOST
Scary.
SadieHOST
[laughs]
SadieHOST
Yep.
NatalieHOST
That is an example of a strong acid because the positive side now has this little spicy water.
SadieHOST
Mm-hmm, and HCl is really scary.
SadieHOST
Like, throughout my career, I've always been worried about coming in contact with HCl.
Jessica BrieckeHOST
up like.
Jessica BrieckeHOST
When people talk about stomach acid, by the way, it's HCL, hydrochloric acid.
Jessica BrieckeHOST
Hello, if you were to get hydrochloric acid on your skin, what's gonna happen? Our stomach is designed to handle that.
Jessica BrieckeHOST
It's an environment where it's supposed to have that.
Kylie BurtonHOST
are so popular what changed It's
Jessica BrieckeHOST
actually a delivery technology that's called SNAC, which is an absorption enhancer, and it does three things at once.
Jessica BrieckeHOST
First, it buffers the acid that I just talked about around the pill so that the peptide doesn't get chewed up in the digestive enzymes and the HCL.
Jessica BrieckeHOST
And it keeps that semaglutide molecule from clumping together so they can actually be absorbed.
Philip PapeHOST
So about nine women per group, kind of a small sample size, I admit, running over eight weeks.
Philip PapeHOST
They use creatine, hydrochloride, or I forget how you pronounce it, the HCL, right? Which is like hydrochloric acid.
Philip PapeHOST
So creatine, HCL, and ethyl ester instead of creatine monohydrate.
Philip PapeHOST
So creatine monohydrate is the form that I recommend people get.
Philip PapeHOST
It's cheap.
Philip PapeHOST
Just find a brand that does third-party testing.
Philip PapeHOST
No form has beaten creatine monohydrate in trials.
Philip PapeHOST
Not HCL, not buffered, not ethyl ester.
Hank GreenHOST
Hydrochloric acid, every chemist's frenemy, as terribly dangerous as it is terribly useful.
Hank GreenHOST
It'll burn your skin, your eyes, even your mucous membranes if you breathe in its fumes for too long.
Hank GreenHOST
But HCl as an acid gives up its hydrogen pretty easily, which makes it good for making things like fertilizers and dyes and even table salt.
Hank GreenHOST
Then there's sodium hydroxide, another substance that I wouldn't wish to be on my worst foe, although I'm glad we have it.
Hank GreenHOST
You might know it as lye, an extremely caustic substance that's used for everything from clearing clogged pipes to purifying drinking water.
14 MINS LATER
Hank GreenHOST
The standard enthalpy of formation for hydrochloric acid is negative 167.2 kilojoules per mole.
Hank GreenHOST
For sodium hydroxide, it's negative 469.15 kilojoules per mole.
Hank GreenHOST
For liquid water, negative 285.8 and for sodium chloride, negative 407.27. I'm not going to do the mole calculations on screen, but trust me when I say that we used 0.100 mole of HCl and the same amount of NaOH.
Ken BerryHOST
So when this chyme, which is the broken up meat, reaches the first part of your small intestine, the duodenum or duodenum, the enzymes are still acting on this meat.
Ken BerryHOST
The pepsin and the hydrochloric acid, the HCL gets neutralized in your small intestine, but then you also have other enzymes called trypsin and chymotrypsin, which continue to break the meat apart in the first part of your small intestine.
Ken BerryHOST
So we're not to the colon yet.
Ken BerryHOST
We're just still in the very first part of the small intestine.
Hank GreenHOST
The molar mass of ammonia, which we call gas A, is 17, and the molar mass of hydrochloric acid, gas B, is 36.
Hank GreenHOST
If we plug those into Graham's Law and set hydrochloric acid's rate of diffusion as 1.0, since we're only looking for a ratio here, we'll find that ammonia's rate of diffusion will be about 1.5 times as fast as that of hydrochloric acid.
Hank GreenHOST
That means that the ammonium chloride should form about three fifths of the way down the tube from the NH3, and about two fifths of the way down from the HCl.
Hank GreenHOST
And there it is.
Hank GreenHOST
See that white cloud? That's the ammonium chloride powder forming.
speaker_3ADVERTISER
in aqueous solution, is always H3O+.
Hank GreenHOST
Let's take a look at the dissociation of hydrochloric acid for some more terminology bits here.
Hank GreenHOST
You see right off the bat that the HCl is donating a proton, but with many acids, particularly weaker acids, the reaction can actually go back the other way, with H3O plus donating its proton.
Hank GreenHOST
So in this situation, every chemical in the reaction, also sometimes called the major species, can be called an acid or a base.
Hank GreenHOST
On the left-hand side, the water is accepting the proton, so it's the base, and HCl is donating it, so it's the acid.
Hank GreenHOST
And on the left-hand side, the Cl- would be accepting the proton, so that would be the conjugate base, and the hydronium ion is the conjugate acid.
speaker_3ADVERTISER
The phrase
Chris BolhuisHOST
And the other thing that you can use to identify dolomite from calcite, 'cause they look very, very similar, is that because of the presence of magnesium in the structure of this mineral, it is less reactive than calcite is.
Chris BolhuisHOST
And so when you put acid on it, you put a drop of HCl on it, it won't fizz.
Chris BolhuisHOST
What you need to do then is take a scissors or a piece of metal and scrape up a little bit of powder, then drop acid on it, and it'll fizz like a flat pop.
Chris BolhuisHOST
It'll just kinda go bubble, bubble, bubble rather than fizzing like crazy like calcite does.
Becca ChilczenkowskiHOST
And so bloating and immune support when traveling.
Becca ChilczenkowskiHOST
I bring digestive enzymes and HCL in particular when I'm traveling.
Becca ChilczenkowskiHOST
I like HCL also with sushi, kind of that extra stomach acid to kind of kill off any potentials.
Becca ChilczenkowskiHOST
Hopefully there aren't, but we always have to be careful if it's raw sushi.
Becca ChilczenkowskiHOST
And any meal on the road, like when you are having larger meals, that is when I continue to take HCL.
Becca ChilczenkowskiHOST
I don't take HCL constantly anymore.
Becca ChilczenkowskiHOST
I have in the past for kind of healing protocols and rebuilding stomach acid levels.
Becca ChilczenkowskiHOST
But now it's just more so when I'm out, when I'm eating larger meals, when we're traveling, when we're having different things.
Stephanie CrasswellerHOST
It is there because you cannot break down food well without it.
Stephanie CrasswellerHOST
So your stomach is going to produce something called HCL.
Stephanie CrasswellerHOST
And when you eat protein like chicken, eggs, Greek yogurt, beef, that acid is going to activate an enzyme called pepsin.
Stephanie CrasswellerHOST
And pepsin is the first enzyme in the chain.
Stephanie CrasswellerHOST
But the mechanism is actually the opposite.
Stephanie CrasswellerHOST
Your food is sitting in your stomach because there isn't enough acid to start the breakdown process.
Stephanie CrasswellerHOST
And so when we don't have adequate HCL, you also are going to Calcium, magnesium, zinc, and those minerals are requiring an acidic environment in order to be pulled from the food and into your bloodstream so you can benefit from it.
Stephanie CrasswellerHOST
This is where a lot of people are now going to be protein deficient despite eating enough protein, mineral deficient despite taking supplementation.
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