Holden Karnofsky
Former CEO of Open PhilanthropyWikipedia
19
MENTIONS
15
EPISODES
14
PODCASTS
Search complete. 19 mentions across 15 episodes found for "Holden Karnofsky".
Oct 19, 2026
Barron's
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22:51Dr. BobHOST
Ms. Tuna is on its board, as is an executive at the trading firm Jane Street.
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22:58Dr. BobHOST
So is Daniela Amadei, who's married to GiveWell's co-founder Holden Karnofsky, now working at Anthropic.
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23:07Dr. BobHOST
Amadei is the co-founder and president of Anthropic and sister of Anthropic CEO Dario Amadei.
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23:16Dr. BobHOST
EA has had some big bang moments, like the implosion of Sam Bankman-Fried and his colleague Caroline Ellison, who met at Jane Street and, motivated by effective altruism, tried to strike it rich and do good with it, or so they claim.
Theo Jaffee: monitoring the "singularity"
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26:27Razib KhanHOST
Well, I will tell you, I don't think I can say this because this is a long time ago.
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26:32Razib KhanHOST
I remember having a long discussion in Holden Karnofsky's car because he was dropping me off to my apartment in Berkeley in 2010.
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26:43Razib KhanHOST
I believe it was the spring.
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26:44Razib KhanHOST
I'm just like thinking of the weather.
We need to talk about 'Effective Altruism'!
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12:15Joe BerquistHOST
That same year, Amodi stumbled on a link on an economic blog that led him to a nonprofit charity evaluator called GiveWell.
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12:24Joe BerquistHOST
Uh, founded the previous year by former Bridgewater Associates hedge fund analyst Holden Karnofsky and Elie Hassenfeld, uh, it aimed to help donors maximize the good done per dollar donated, usually measured in lives saved.
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12:40Joe BerquistHOST
Uh, Amodi began leaving comments on the GiveWell blog and once guest blogged on it directly.
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12:46Joe BerquistHOST
In the 2010 post, uh, he deployed utilit-utilitarian reasoning while weighing whether to give 10,000 to one charity rather than another.
Why Top AI Creators Are Prepping For The End Of The World
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17:19speaker_4HOST
Yes.
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17:19speaker_4HOST
GiveWell was a charity evaluator founded by a man named Holden Karnofsky.
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17:23speaker_4HOST
Karnofsky was basically the central hub, the chief accountant for the early effective altruism movement.
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17:30speaker_3HOST
So you have this collision of titans.
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19:09speaker_4HOST
You had Chris Ola, another foundational, globally recognized AI researcher.
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19:15speaker_1ADVERTISER
Wow.
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19:15speaker_4HOST
And of course, Holden Karnofsky, who would later marry Daniela Amidoy and become Dario's brother-in-law.
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19:20speaker_4HOST
It was a closed loop of the highest IQ individuals in the Bay Area.
The AI Doomsday Preppers | 9th Oct 2026
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3:23speaker_1HOST
And you have a Princeton physics PhD student named Dario Amadei, who is heavily absorbing Yudkowsky's probability models back in 2008.
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3:32speaker_0HOST
And she eventually connected with Holden Karnofsky, who co-founded a charity evaluator called GiveWell.
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3:38speaker_1HOST
Yeah, and by 2013, Karnofsky had literally moved into Amodei's group house near Glen Park in San Francisco.
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3:44speaker_0HOST
So that Glen Park house was effectively the incubator for the modern AI safety movement.
“Eccentrically Effective” by William_MacAskill
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5:04Type 3 AudioNARRATOR
I agree, and effective altruists have been saying so for years.
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5:09Type 3 AudioNARRATOR
In 2022 Holden Karnofsky, a co-founder of GiveWell, wrote, I think it's a bad idea to embrace the core ideas of EA without limits or reservations.
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5:19Type 3 AudioNARRATOR
We as EAs need to constantly inject pluralism and moderation.
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5:23Type 3 AudioNARRATOR
My own PhD focused on moral uncertainty.
In 2023 Ajeya Cotra already knew what was coming (classic episode)
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3:13Rob WiblinHOST
Yeah.
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3:14Rob WiblinHOST
Is it basically all AI all, all the time these days? I think o- one of your colleagues, Holden Karnofsky, who's also been on the show before, uh, used to work on a wider range of issues, but recent, recent events have prompted him to narrow his focus somewhat.
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3:26Rob WiblinHOST
Has, has the same happened to you?
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3:27Ajeya CotraGUEST
Certainly for me, it's all AI all the time, and it has been for three years or so.
1 HR 51 MINS LATER
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114:46Rob WiblinHOST
... that's working on practical tests for whether a model is safe that potentially could be applied to all kinds of models, uh, b- before they get deployed.
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114:55Rob WiblinHOST
And I think the, the hope that they have is that AI labs would, you know, voluntarily sign on to follow a kind of standards and certification program where models above any particular size would have to be stress-tested, I guess, in, in all these kinds of different ways to ensure that they're not gonna engage in behaviors that, that we don't like.
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115:12Rob WiblinHOST
I think there, there's a decent amount of buzz around this effort and people, uh, who are helping with include Beth Barnes, who I'm hoping to interview later in the year, and Holden Karnofsky and Paul Christiano, who've been on the show before.
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115:22Rob WiblinHOST
I, I guess we should say that, uh, I think, uh, you and Paul are, are, are an item, so.
Larry Ellison’s Media Ambitions & Kevin Roose on AI’s Biggest Gamble
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29:58Kevin RooseGUEST
Daniela Amodei, now Anthropic's president.
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30:00Kevin RooseGUEST
Holden Karnofsky, her husband now.
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30:03Kevin RooseGUEST
Um, Chris Olah, Paul Christiano, like all these sort of names from, uh, AI-
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30:08Peter KafkaHOST
All lived in one house
Inside Jensen Huang’s Son-in-Law’s Rise at Nvidia, Anthropic’s Sizable IPO Charity Bill
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38:06Cory WeinbergCORRESPONDENT
I don't know.
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38:06Cory WeinbergCORRESPONDENT
I think about it in the orbit of, of like, uh, effective altruism, like sort of people who are interested in like money ball for charity sort of ideas of like, you know, what, what's like the most effective use of this dollar? So, um, uh, Daniela Almada's husband, Holden Karnofsky, was previously, you know, the founder of, of GiveWell, you know, sort of this platform for, you know, ch- channeling donations towards the most effective causes.
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38:34Cory WeinbergCORRESPONDENT
Um, uh, their early...
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38:37Cory WeinbergCORRESPONDENT
You know, Dario and Daniela themselves have been very involved with GiveWell and kind of philanthropic type of organizations for, for a long time.
Nitasha Tiku: Self-Regulation, Rogue Agents & Mainstreaming the AI Apocalypse
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40:18John HeilemannHOST
Right.
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40:18Nitasha TikuGUEST
The head of it is married to his sister, Holden Karnofsky.
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40:22Nitasha TikuGUEST
He works at Anthropic.
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40:24Nitasha TikuGUEST
Um, Dario was roommates with him, um, early on in, in his, uh, like, stint in the tech industry.
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