HLA-DQ8

Your report covers lactose tolerance, the LCT gene, which tells you whether you genuinely can't process dairy or whether something else is going on.

It covers HLA-DQ2.5 and HLA-DQ8.

These are the celiac-associated genes.

So it's not a celiac diagnosis, but it tells you whether you carry the genetic susceptibility at all, which is enormously useful information if you've been going around in circles with gluten.

And then the other piece that I find, and I think a lot of people listening can relate, is because so many people with Hashimoto's do better gluten-free.

Now, again, it's not for every person, but generally speaking, right? In addition to potentially even celiac, also just having the DQ2 and DQ8.

And there's so many other immune things, right? That it can lower inflammation.

So people go gluten-free.

Just be careful not to choose, you know, manufactured gluten-free products." But because, as you know very well, this will open a, a, a Pandora vase of, uh, you know, they lack fiber, they lack, uh, micronutrients and so forth and so on.

But anyway, on the other hand, if the patient is HLA-DQ2 or DQ8 positive, then it's, it's hard.

Then it's hard.

You have to convince this patient to undergo a gluten challenge.

But we do see a subset that don't tolerate gluten.

We don't know if they have celiac or not.

In some of the cases that we see, they have the celiac genes, the DQ2 and DQ8 gene.

In some of the patients we see, they don't have the genes.