HEK293
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Search complete. 2 mentions across 1 episode found for "HEK293".
Sep 29, 2026
TWiN 75: Arc, tau, and Alzheimer's
J
37:27Jason ShepherdGUEST
... yep.
J
37:27Jason ShepherdGUEST
So this is where... 'Cause we, we had-- You know, obviously, that was the first thing we looked at and, uh, in he- in HEK cells.
V
37:34Vincent RacanielloHOST
Mm.
J
37:34Jason ShepherdGUEST
The first evidence that we had was that if you knock down their ESCRTs, Arf still gets released.
V
39:32Vincent RacanielloHOST
Hmm.
J
39:33Jason ShepherdGUEST
Um, and in that-- And when it does that, that's when you start to recruit the, the, the whole thing into a vesicle.
J
39:41Jason ShepherdGUEST
Um, the other thing that we didn't throw into the paper but we're sort of, you know, looking at now is that when you overexpress both of those proteins in a HEK cell, for example, they form condensates, these, you know, liquid-
V
39:52Vincent RacanielloHOST
Mm-hmm