So given that these are the same or similar behaviors, you know, what do you think accounts for that split, that difference?

Yeah, it's interesting because as we have these trials, whether it be the finger trial, the US pointer trial, the Latin American fingers trial, and others that have demonstrated a benefit on cognition and a population at risk for cognitive decline with behavior change.

And again, that that structure and support matter and provide a greater benefit.

We are following those individuals over a longer period of time to really understand what that impact is on dementia risk.

You know, I do think that some of it, some of it is where is the data? Where's the strength of the data? The data tell us that lifestyle behaviors, that this behavioral change is very important for maintaining brain health.

There's an impact on cognition for individuals.

But understanding, are we able to reduce risk of Alzheimer's specifically or delay onset of dementia, any of the causes of dementia? That's really the next question that we're asking.

And so what does that tell you about where public health efforts should go next or where the association is pushing?

Heather Snyder from Alzheimer's Association has been helping both studies almost since their inception.

U.S. Pointer had a similar result in terms of seeing the greater benefit in a structured intervention compared to a self-guided intervention in an at-risk population.

And in fact, the Latin American Finger Study and US Pointer, we think of them as sister trials.

They really have worked hand in hand since the very, very beginning.

US Pointer was actually first announced that we were going to do that study in 2017.

And it was very quickly after that we all started to have conversations and discussions around where we go and what this could look like as a sister trial.

And so I think we are here today now to have really back to back, one year apart, these two studies reporting out.

Can you help clarify to our listeners what is Alzheimer's disease, and how does that fit into the broader category of dementia?

A good way to think about it is dementia is that umbrella.

It's the symptoms a person is experiencing.

It's the changes of memory, thinking, reasoning that are impacting an individual's daily life and ultimately their dependence.

Alzheimer's disease is specific brain changes, and it is the most common form of dementia.

Our brains are this complex organ that are made up of so many pieces and parts.

There are over a hundred billion nerve cells, and these brain cells have very specialized jobs that allow our brains to really function as this control center.

But are we close to finding a cure?