Haloperidol
MedicationWikipedia
32
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21
EPISODES
21
PODCASTS
Search complete. 32 mentions across 21 episodes found for "Haloperidol".
Sep 13, 2026
Ella MacduffGUEST
And so I slept it off.
Ella MacduffGUEST
They ended up giving me a shot of Haldol, which is a sedative, because I was very aggressive at the time.
Ella MacduffGUEST
So the combination of anxiety medication that I was already on, Haldol, which was the sedative, and the drug that was in my system because somebody drugged me, gave me something called serotonin syndrome.
Ella MacduffGUEST
And so the next day after being released, I was rushed back to the hospital and put into the ICU.
Ella MacduffGUEST
And that was such a scary experience, and I also for the longest time felt like it was my fault what happened to me.
Jennifer WoodardGUEST
Then you're looking at which of these worked.
Jennifer WoodardGUEST
Am I double dosing or getting false equivalencies? The old reliable that I personally use less in my current institution is Haldol or Heliperidol.
Jennifer WoodardGUEST
This is also available in oral IM and IV forms.
Jennifer WoodardGUEST
We use this a little less now, I think, because it tends to be more QT prolonging and has that extra risk of tardive dyskinesia side effects.
Gardiner HarrisGUEST
So Johnson & Johnson, um, entered the drug business actually in 1960, when it bought both, uh, Janssen Pharmaceutica, the sort of the named company of this great medicinal chemist, Paul Janssen, and, um, McNeil Laboratories, which made Tylenol.
Gardiner HarrisGUEST
And Paul Janssen had developed something called Haldol, which was part of the original group of what are now known as antipsychotics.
Gardiner HarrisGUEST
They originally were known as major tranquilizers.
Gardiner HarrisGUEST
The first of these was the famous drug Thorazine.
Gardiner HarrisGUEST
And one of the only ways known to sort of knock that down and get people back to reality is for them to take, um, these medicines.
Gardiner HarrisGUEST
But the problem with these medicines, as people began to realize in the 1960s, um, at these psychiatric hospitals, as soon as Thorazine started to be widely used, a huge share of these patients started getting diabetes, um, started getting fat.
Gardiner HarrisGUEST
Um, and so Johnson & Johnson, when its patent on Haldol ran out, they knew that the, that the thing that they wanted was a drug that did as well in knocking down hallucinations, but didn't have as bad a side effect as Haldol and Thorazine.
Gardiner HarrisGUEST
And the worst side effect of those drugs, what was called extrapyramidal side effects, which is twitches-
ToddHOST
I'm sitting here trying to think of if I know of a study before this one that directly compares dexmedetomidine with an antipsychotic.
ToddHOST
And I know of some studies that involve either of those, like you've commented on, and also – MindUSA is an antipsychotic study, but it compares Haldol, Ziprazidone, and placebo.
EddieHOST
So typical versus atypical antipsychotics.
EddieHOST
Correct.
JohnHOST
Walker, Texas Ranger.
JamieHOST
The documented history of Andrea's psychiatric collapse, the 1999 hospitalizations, the explicit warning of her, if you have another kid, this will come back, the decision to have a fifth child anyway, the Haldol discussion, and the fact that it was discontinued shortly before the death of the kids, the filled bathtub on May 3rd where she expressed, I'm going to drown my kids, and then the discharge while she was under suicide watch.
JamieHOST
All this came out again in full, and this jury got to see all of it again without Park Dietz's testimony.
JamieHOST
The defense's expert was Dr. Philip Resnick, who is a professor of psychiatry at Case Western Reserve University, who specializes in filicide, which is the killing of children by parents we've discussed before, and who testified that Andrea Yates was was in the grip of a severe psychotic delusion at the time of the drowning.
ChrisSOUNDBITE_SPEAKER
for a few years.
ChrisSOUNDBITE_SPEAKER
And, dude, the side effects are so much worse than the actual, like, on Haldol.
ChrisSOUNDBITE_SPEAKER
You go to eat, like, you're shaking so bad the food will fall off your forehead.
ChrisSOUNDBITE_SPEAKER
With Thorazine, you're so tired all the time, you feel like a zombie, and you're just not yourself.
Casey JordanGUEST
You've got the signs, you've got the time in a mental institution, you've got the suicide attempts, you have all the warning signs.
Casey JordanGUEST
I mean, Andrea Yates was on Haldol, one of the strongest antipsychotic drugs you could possibly give her, and yet she still had more children, which makes you wonder if she really wanted to have those children.
Casey JordanGUEST
Was she enough conscientious about her choices? The point is, Lindsay Clancy, by comparison, not only had all the same signs, but was probably not even getting the level of mental health care that Andrea Yates was, apart from the fact that she was prescribed 14 drugs by all these different doctors.
Casey JordanGUEST
That whole idea that you can't plan when you're psychotic, Andrea Yates proves that you can.
Lane PeytonGUEST
Thank God he didn't have kids.
Lane PeytonGUEST
Since then, he's been living in his parents' house, often on the crappy meds, Haldol and Vega.
Lane PeytonGUEST
You know, like it works, but I'm getting fat and my mind doesn't work.
Lane PeytonGUEST
So like often on compliance.
Early BrunnerHOST
Yeah.
Early BrunnerHOST
So then I left the psych ward on five different psychiatric medications, some of them like, you know, pretty intense, you know, Haldol and things like that.
Early BrunnerHOST
And over the next few years, it was like, you know, lower this dose, increase this dose, switch to this drug, switch to that other drug.
Early BrunnerHOST
And then in the end, when I got into long term recovery from substance use, I All of the symptoms of having bipolar disorder just vanished.
Sasha Altman DeBruleGUEST
And, you know, the philosophy at the time was like, you know, the break that people are going through is like actually important.
Sasha Altman DeBruleGUEST
It's like this idea of like a breakdown to a breakthrough.
Sasha Altman DeBruleGUEST
And if you just stick someone on a bunch of Haldol, it stops the process in the middle and then they can't get to the other side of it.
Sasha Altman DeBruleGUEST
And I don't know, I've spent years thinking about that because I wonder what it would have been like to have ended up in some other kind of situation.
Chris NathanHOST
After she's released, she reportedly holds a knife to her throat and has to be hospitalized again.
Chris NathanHOST
And eventually, doctors put her on Haldol.
Chris NathanHOST
Haldol is a powerful antipsychotic.
Chris NathanHOST
And it seems to work.
Chris NathanHOST
Andrea improves, but her psychiatrist sees the bigger problem.
Chris NathanHOST
At one point she stops feeding baby Mary and once again, Andrea ends up in a psychiatric hospital.
Chris NathanHOST
She's discharged, then she's readmitted.
Chris NathanHOST
And during that second hospitalization, she's put back on Haldol.
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