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Glutathione peroxidase 1

Glutathione peroxidase 1

Search complete. 2 mentions across 2 episodes found for "Glutathione peroxidase 1".

Sep 18, 2026

Lisa TamatiHOST
25:57
And there are three more that almost never get discussed and that I think are among the most important genes on any panel.
Lisa TamatiHOST
26:05
One is MN-SOD, S-O-D, manganese superoxide dismutase, and then GPX-1, which is glutathione peroxidase, and CAT, or catalase.
Lisa TamatiHOST
26:16
These three are the cleanup crew inside your mitochondria, and what they do is remarkable.
Lisa TamatiHOST
26:22
So your mitochondria produce about 95% of the free radicals in your body.
Jonathan KilGUEST
41:44
So we think we have one of the first validated drug targets.
Jonathan KilGUEST
41:48
It's called glutathione peroxidase 1.
Jonathan KilGUEST
41:51
And GPX1 is, again, highly expressed in the cochlea.
Jonathan KilGUEST
41:58
It's highly expressed in areas of the brain that control behavior and some executive function, then lung and kidney.
Jonathan KilGUEST
42:06
So we think we have broad applicability even beyond the inner ear.

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